Results 51 to 60 of about 25,082,508 (331)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Problem for hyperbolic system of equations having constant coefficients with integral conditions with respect to the time variable

Karpatsʹkì Matematičnì Publìkacìï, 2014
In a domain specified in the form of a Cartesian product of a segment $\left[0,T\right]$ and the space ${\mathbb R}^{p}$, we study a problem with integral conditions with respect to the time variable for  hyperbolic system with constant coefficients in a
A.M. Kuz, B.Yo. Ptashnyk
doaj   +1 more source

Quasilinear hyperbolic systems [PDF]

Communications in Mathematical Physics, 1979
We construct global solutions for quasilinear hyperbolic systems and study their asymptotic behaviors. The systems include models of gas flows in a variable area duct and flows with a moving source. Our analysis is based on a numerical scheme which generalizes the Glimm scheme for hyperbolic conservation laws.
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Water ow on vegetated hill. 1D shallow water equation type model

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
A mathematical model for the water ow on a hill covered by variable distributed vegetation is proposed in this article. The model takes into account the variation of the geometrical properties of the terrain surface, but it assumes that the surface ...
Ion Stelian, Marinescu Dorin, Ion Anca Veronica, Cruceanu Stefan Gicu, Iordache Virgil   +4 more
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Hyperbolic Stefan problem with nonlocal boundary conditions

Математичні Студії
In this paper, we consider problems with unknown boundaries for hyperbolic equations and systems with free boundaries with two independent variables. The boundary conditions for such equations in the linear or quasilinear cases are given in nonlocal (non-
V. Kyrylych, G. Beregova, O. Milchenko
doaj   +1 more source

Einstein-Bianchi hyperbolic system for general relativity [PDF]

, 1997
We consider the evolution part of the Cauchy problem in General Relativity [8] as the time history of the two fundamental forms of a spacelike hypersurface: its metric g and its extrinsic curvature K. On such a hypersurface, for example an “initial” one,
A. Anderson, Y. Choquet-bruhat, J. York, Jr.   +3 more
semanticscholar   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source