Results 141 to 150 of about 98,203 (376)

A Controlled Increase in Dietary Phosphate Elevates BP in Healthy Human Subjects. [PDF]

open access: yes, 2018
Background Despite epidemiologic evidence for increased cardiovascular morbidity and mortality associated with both high dietary and serum phosphate in humans with normal renal function, no controlled phosphate intervention studies of systemic ...
Bestmann, Lukas   +4 more
core  

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications

open access: yesClinical Ophthalmology, 2017
Jie Shen,1 Margot L Goodkin,2 Warren Tong,2 Mayssa Attar3 1Clinical Pharmacology, 2Clinical Development, 3Clinical Pharmacology, Metabolism and Immunology, Allergan plc, Irvine, CA, USA Purpose: Fixed-combination medications can benefit patients ...
Shen J, Goodkin ML, Tong W, Attar M
doaj  

Modified preputial elevation and cranial translation of the prepuce by transection of the skin caudal to the bulbus glandis for managing chronic idiopathic paraphimosis in dogs: six cases (2021‐2024)

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To report the signalment, clinical signs, duration of clinical signs, length of penile protrusion, surgical technique (modified preputial elevation and cranial translation of the prepuce), length of preputial advancement, postoperative complications, outcomes and long‐term postoperative follow‐up.
I. P. Thyriakis   +5 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

open access: yesJournal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes   +14 more
wiley   +1 more source

Coronary Reactive Hyperemia [PDF]

open access: yes, 2007
Introduction: The mechanism of post ischemic reactive hyperemia is still unknown but now thought to be multifactorial and perhaps involving purinergic signalling. Purines such as ATP and ADP have recently been discovered to play a vital role in the regulation of vascular tone.
openaire   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry   +5 more
wiley   +1 more source

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