Results 141 to 150 of about 58,651 (301)

Modulatory effects of noradrenergic and serotonergic signaling pathway on neurovascular coupling

Communications Biology
Dynamic changes in astrocyte Ca2+ are recognized as contributors to functional hyperemia, a critical response to increased neuronal activity mediated by a process known as neurovascular coupling (NVC).
Robert B. Renden, Adam Institoris, Kushal Sharma, Cam Ha T. Tran   +3 more
doaj   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow

Nature Communications
Hyperemia in response to neural activity is essential for brain health. A hyperemic response delivers O2 and nutrients, clears metabolic waste, and concomitantly exposes cerebrovascular endothelial cells to hemodynamic forces.
Xin Rui Lim, Mohammad M. Abd-Alhaseeb, Michael Ippolito, Masayo Koide, Amanda J. Senatore, Curtis Plante, Ashwini Hariharan, Nick Weir, Thomas A. Longden, Kathryn A. Laprade, James M. Stafford, Dorothea Ziemens, Markus Schwaninger, Jan Wenzel, Dmitry D. Postnov, Osama F. Harraz   +15 more
doaj   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Acute cardiovascular changes following heat exposure during simulated shipboard firefighting

Experimental Physiology, EarlyView.
Abstract Like structural firefighting, shipboard firefighting requires extreme exertion. However, shipboard firefighting may be a unique cardiovascular stress as most sailors lack extensive firefighting experience and may complete significant work before reaching the fire scene.
Daniel K. Sweet, Elizabeth M. Lavoie, Hayden W. Hess, Stuart Inglis, Brian Monaco, J. Luke Pryor, Steven E. Reis, David Hostler   +7 more
wiley   +1 more source

Lower limb blood flow responses during higher‐ and lower‐load bilateral leg press exercise

Experimental Physiology, EarlyView.
Abstract The local blood flow response to resistance exercise (RE) is complicated by local muscular contractions and large swings in perfusion pressure. The magnitude of these responses might vary according to exercise intensity, number of sets and number of repetitions, and as a result, the local shear environment during RE remains uncharacterized. We
Eudoxia Zafiris, Jeremy. N. Cohen, Tania J. Pereira, Jason S. Au   +3 more
wiley   +1 more source

The effect of repeated hot water immersion on microvascular function, glycaemic control and inflammation in White European and South Asian males

Experimental Physiology, EarlyView.
Abstract Individuals of South Asian (SA) descent display a higher risk for cardiovascular disease and type 2 diabetes mellitus than their White European (WE) counterparts. Heat therapy, such as hot water immersion (HWI), can improve microvascular function and glycaemic control, although effects across racial groups are unknown.
David Bellini, Alex Lloyd, Christof A. Leicht, Stephen J. Bailey, Lewis J. James, Matthew J. Maley   +5 more
wiley   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Absorptive hyperemia

Gastroenterology, 1995
openaire   +2 more sources

Vascular and skeletal muscle oxidative capacity responses to continuous double and single leg cycling

Experimental Physiology, EarlyView.
Abstract The purpose of this work was to determine endothelial, microvascular, skeletal muscle oxidative capacity (SMOC) and cardiorespiratory responses to an acute bout of continuous single leg cycling (SLC) and double leg cycling (DLC). Ten recreationally active men and women volunteered to participate in this investigation and reported to the ...
Edward Z. Pelka, B. Ryan Davis, John McDaniel   +2 more
wiley   +1 more source