Results 71 to 80 of about 98,203 (376)

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Near-infrared spectroscopy study of tourniquet-induced forearm ischaemia in patients with coronary artery disease [PDF]

, 2001
Near-Infrared Spectroscopy (NIRS) can be employed to monitor local changes in haemodynamics and oxygenation of human tissues. A preliminary study has been performed in order to evaluate the NIRS transmittance response to induced forearm ischaemia in ...
Bavera, Matteo, Corti, Mario, Falcone, Colomba, Giardini, Mario Ettore, Guizzetti, Giovanni G., Lago, Paolo, Pastore, Federico   +6 more
core   +4 more sources

Non-Ischemic Cerebral Energy Dysfunction at the Early Brain Injury Phase following Aneurysmal Subarachnoid Hemorrhage

Frontiers in Neurology, 2017
BackgroundThe pathophysiology of early brain injury following aneurysmal subarachnoid hemorrhage (SAH) is still not completely understood.ObjectiveUsing brain perfusion CT (PCT) and cerebral microdialysis (CMD), we examined whether non-ischemic cerebral ...
Laurent Carteron, Laurent Carteron, Camille Patet, Camille Patet, Daria Solari, Daria Solari, Mahmoud Messerer, Roy T. Daniel, Philippe Eckert, Reto Meuli, Mauro Oddo, Mauro Oddo   +11 more
doaj   +1 more source

Time course of conjunctival hyperemia induced by omidenepag isopropyl ophthalmic solution 0.002%: a pilot, comparative study versus ripasudil 0.4%

BMJ Open Ophthalmology, 2020
Objective We investigated the detailed time course of conjunctival hyperemia induced by omidenepag isopropyl ophthalmic solution 0.002% (omidenepag), a selective prostaglandin E2 receptor 2 agonist.Methods and analysis We recruited 34 healthy subjects ...
Yoshiaki Kiuchi, Ryo Asaoka, Shunsuke Nakakura, Etsuko Terao, Yasuko Fujisawa, Yuki Nagata, Kanae Ueda, Yui Kobayashi, Satomi Oogi, Saki Dote, Miku Shiraishi, Hitoshi Tabuchi, Tsuyoshi Yoneda, Atsuki Fukushima   +13 more
doaj   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]

, 2004
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Davies, N.A., Hayes, P.C., Jalan, R., Lee, A., Mookerjee, R.P., Shawcross, D.L., Williams, R.   +6 more
core  

Hybrid Equation/Agent-Based Model of Ischemia-Induced Hyperemia and Pressure Ulcer Formation Predicts Greater Propensity to Ulcerate in Subjects with Spinal Cord Injury [PDF]

, 2013
Pressure ulcers are costly and life-threatening complications for people with spinal cord injury (SCI). People with SCI also exhibit differential blood flow properties in non-ulcerated skin.
A Solovyev, A Stefanovska, AB Jackson, Alexey Solovyev, AM Bailey, AT Onigbinde, David Brienza, DHJ Thijssen, DHJ Thijssen, E Linder-Ganz, EA Neugebauer, FF de Mul, FFM de Mul, G An, G An, G An, G An, H Kitano, IN Athanasiadis, J Hart, J Hart, J Tang, J Tang, JL Segal, JM Epstein, JR Bethea, JR Bethea, L Giangregorio, L Zhang, M Kooijman, M Kosiak, M Noble, MJ Castro, MJ Devivo, NY Li, P de Groot, PG Popovich, Q Mi, Qi Mi, RW Teasell, S Hagisawa, S Marino, S Sprigle, Shayn M. Peirce, SM Peirce, T Tjardes, TG Buchman, TG Buchman, V Schubert, W Sae-Sia, Y Chen, Y Mansury, Y Vodovotz, Y Vodovotz, Y Vodovotz, Yi-Ting Tzen, Yoram Vodovotz, Z Guo   +57 more
core   +3 more sources

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]

, 2017
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin, McClure, John D., Oldroyd, Keith G.   +2 more
core   +1 more source

Reactive hyperemia increases forearm vein area [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2006
To determine the effect of reactive hyperemia on human forearm vein area.After obtaining ethics approval and informed consent, an automatic tourniquet was applied to the forearms of 20 healthy subjects for one, two, and three minutes, at pressures of 25 mmHg, 200 mmHg, then 25 mmHg.
Heather L, Mollison, William P S, McKay, Rajesh H, Patel, Stefan, Kriegler, October E, Negraeff   +4 more
openaire   +2 more sources