Results 11 to 20 of about 20,309 (259)
Impact of sotagliflozin on glomerular hyperfiltration in people with type 1 diabetes: A post hoc analysis of the inTandem3 trial. [PDF]
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1537-1540, February 2026.
Pathak A +4 more
europepmc +2 more sources
Hyperfiltration and Metabolism Before and After a Low-Calorie, Pre-Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs. [PDF]
ABSTRACT Psychotropic drug concentrations increase/decrease with hydrophilicity/lipophilicity after a low‐calorie pre‐bariatric surgery diet. To investigate underlying mechanisms, body weight and serum creatinine/cystatin C changes over the diet period were characterized and suggested to reflect changes in glomerular filtration and metabolic capacity ...
Axelsson MAB, Wallerstedt SM.
europepmc +2 more sources
Hyperfiltration, traditionally defined as a supraphysiologic elevation in GFR, has been implicated in kidney disease pathogenesis since 1931. Then, Jolliffe and Smith ([1][1]) demonstrated that dogs maintained on a pure beef diet had substantial increases in their creatinine clearances ...
Sri Lekha, Tummalapalli +1 more
openaire +2 more sources
Renal Hyperfiltration and the Development of Microalbuminuria in Type 1 Diabetes [PDF]
OBJECTIVE: The purpose of this study was to examine prospectively whether renal hyperfiltration is associated with the development of microalbuminuria in patients with type 1 diabetes, after taking into account known risk factors.
Aschengrau, Ann +6 more
core +6 more sources
Purpose: Vancomycin is a narrow therapeutic window glycopeptide antibiotic that acts against Gram-positive bacteria. As it is renally eliminated, therapeutic drug monitoring is recommended for vancomycin, especially in case of kidney function alteration.
Zahra Sahraei +9 more
doaj +1 more source
ObjectiveThis study aimed to explore the relationship between short-term (≤12 months) changes in the estimated glomerular filtration rate (eGFR) and hemoglobin A1c (HbA1c) in patients with type 2 diabetes (T2D).MethodA total of 2,599 patients with T2D ...
Lingwang An +9 more
doaj +1 more source
Glomerular hyperfiltration is associated with dementia: A nationwide population-based study.
BACKGROUND:Glomerular hyperfiltration may be a clinical phenotype of endothelial dysfunction. Endothelial dysfunction may cause vascular dementia through the deterioration of cerebral blood flow.
Min Woo Kang +15 more
doaj +1 more source
Glomerular filtration rate abnormalities in sickle cell disease
Sickle cell disease (SCD) is a group of inherited blood disorders affecting the β-globin gene, resulting in the polymerization of hemoglobin and subsequent sickling of the red blood cell.
Nowah Afangbedji, Marina Jerebtsova
doaj +1 more source
SGLT2 Inhibitors and the Diabetic Kidney [PDF]
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca +4 more
core +1 more source
Background: Glomerular hyperfiltration is one physiological adaptation to pregnancy, marked by a decline in serum creatinine (SCr) concentration by 16 weeks’ gestation.
Ziv Harel, Alison L. Park, Joel G. Ray
doaj +1 more source

