Results 11 to 20 of about 20,309 (259)

Impact of sotagliflozin on glomerular hyperfiltration in people with type 1 diabetes: A post hoc analysis of the inTandem3 trial. [PDF]

open access: yesDiabetes Obes Metab
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1537-1540, February 2026.
Pathak A   +4 more
europepmc   +2 more sources

Hyperfiltration and Metabolism Before and After a Low-Calorie, Pre-Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
ABSTRACT Psychotropic drug concentrations increase/decrease with hydrophilicity/lipophilicity after a low‐calorie pre‐bariatric surgery diet. To investigate underlying mechanisms, body weight and serum creatinine/cystatin C changes over the diet period were characterized and suggested to reflect changes in glomerular filtration and metabolic capacity ...
Axelsson MAB, Wallerstedt SM.
europepmc   +2 more sources

Hyperfiltration [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2019
Hyperfiltration, traditionally defined as a supraphysiologic elevation in GFR, has been implicated in kidney disease pathogenesis since 1931. Then, Jolliffe and Smith ([1][1]) demonstrated that dogs maintained on a pure beef diet had substantial increases in their creatinine clearances ...
Sri Lekha, Tummalapalli   +1 more
openaire   +2 more sources

Renal Hyperfiltration and the Development of Microalbuminuria in Type 1 Diabetes [PDF]

open access: yes, 2009
OBJECTIVE: The purpose of this study was to examine prospectively whether renal hyperfiltration is associated with the development of microalbuminuria in patients with type 1 diabetes, after taking into account known risk factors.
Aschengrau, Ann   +6 more
core   +6 more sources

Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial

open access: yesFrontiers in Pharmacology, 2022
Purpose: Vancomycin is a narrow therapeutic window glycopeptide antibiotic that acts against Gram-positive bacteria. As it is renally eliminated, therapeutic drug monitoring is recommended for vancomycin, especially in case of kidney function alteration.
Zahra Sahraei   +9 more
doaj   +1 more source

The Association Between the Decline of eGFR and a Reduction of Hemoglobin A1c in Type 2 Diabetic Patients

open access: yesFrontiers in Endocrinology, 2022
ObjectiveThis study aimed to explore the relationship between short-term (≤12 months) changes in the estimated glomerular filtration rate (eGFR) and hemoglobin A1c (HbA1c) in patients with type 2 diabetes (T2D).MethodA total of 2,599 patients with T2D ...
Lingwang An   +9 more
doaj   +1 more source

Glomerular hyperfiltration is associated with dementia: A nationwide population-based study.

open access: yesPLoS ONE, 2020
BACKGROUND:Glomerular hyperfiltration may be a clinical phenotype of endothelial dysfunction. Endothelial dysfunction may cause vascular dementia through the deterioration of cerebral blood flow.
Min Woo Kang   +15 more
doaj   +1 more source

Glomerular filtration rate abnormalities in sickle cell disease

open access: yesFrontiers in Medicine, 2022
Sickle cell disease (SCD) is a group of inherited blood disorders affecting the β-globin gene, resulting in the polymerization of hemoglobin and subsequent sickling of the red blood cell.
Nowah Afangbedji, Marina Jerebtsova
doaj   +1 more source

SGLT2 Inhibitors and the Diabetic Kidney [PDF]

open access: yes, 2016
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca   +4 more
core   +1 more source

Association Between Blunted Glomerular Hyperfiltration in Pregnancy and Severe Maternal Morbidity—A Research Letter

open access: yesCanadian Journal of Kidney Health and Disease, 2021
Background: Glomerular hyperfiltration is one physiological adaptation to pregnancy, marked by a decline in serum creatinine (SCr) concentration by 16 weeks’ gestation.
Ziv Harel, Alison L. Park, Joel G. Ray
doaj   +1 more source

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