Results 51 to 60 of about 18,414 (250)

The Relationship of Alcohol Consumption and Drinking Pattern to the Risk of Glomerular Hyperfiltration in Middle-aged Japanese Men: The Kansai Healthcare Study

Journal of Epidemiology
Background: Glomerular hyperfiltration has been reported to be associated with adverse renal outcomes in the general population. It is not known whether drinking pattern is associated with the risk of glomerular hyperfiltration in healthy individuals ...
Mikiko Shibata, Kyoko Kogawa Sato, Hideo Koh, Izumi Shibata, Kaori Okamura, Yuka Takeuchi, Keiko Oue, Michio Morimoto, Tomoshige Hayashi   +8 more
doaj   +1 more source

Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney

Cells, 2021
Increased fluid flow shear stress (FFSS) in solitary kidney alters podocyte function in vivo. FFSS-treated cultured podocytes show upregulated AKT-GSK3β-β-catenin signaling.
Tarak Srivastava, Daniel P. Heruth, R. Scott Duncan, Mohammad H. Rezaiekhaligh, Robert E. Garola, Lakshmi Priya, Jianping Zhou, Varun C. Boinpelly, Jan Novak, Mohammed Farhan Ali, Trupti Joshi, Uri S. Alon, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Ram Sharma, Mark L. Johnson, Mukut Sharma   +17 more
doaj   +1 more source

Plant food in а diet, vegetarianism and kidney function

Počki, 2023
A vegetarian diet as a common dietary pattern in the real world is an attractive target for study. Previous studies from different years have shown that a vegetarian diet is associated with a reduced risk of chronic kidney disease progression and a ...
I.I. Melnyk
doaj   +1 more source

The Impact of Augmented Renal Clearance on the Pharmacokinetics of Levetiracetam in Critically Ill Patients: A Literature Review

The Journal of Clinical Pharmacology, EarlyView.
Abstract Levetiracetam is an antiseizure medication (ASM) that has several advantages over other ASMs, such as dose‐proportional pharmacokinetics, high bioavailability, and minimal drug interactions. The drug is primarily eliminated through the kidneys. Therefore, dose adjustments are necessary in patients with renal impairment or patients experiencing
Maged Kharouba, Asma Aboelezz, Janice Y. Kung, Sherif Hanafy Mahmoud   +3 more
wiley   +1 more source

Kidney Hyperfiltration After Nephrectomy: A Mechanism to Restore Kidney Function in Living Donors

Acta Medica Indonesiana, 2020
Living donor kidney transplantation (LDKT) is the treatment of choice for patients with end stage renal disease (ESRD). Up to now, the studies reporting the impact of nephrectomy in living kidney donors to their future kidney function were limited.
Maruhum Bonar Marbun, Endang Susalit
doaj  

Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E₂ Activation in Human Podocytes

Cells, 2020
Glomerular hyperfiltration is an important mechanism in the development of albuminuria. During hyperfiltration, podocytes are exposed to increased fluid flow shear stress (FFSS) in Bowman’s space.
Eva Mangelsen, Michael Rothe, Angela Schulz, Aikaterini Kourpa, Daniela Panáková, Reinhold Kreutz, Juliane Bolbrinker   +6 more
doaj   +1 more source

The hyperfiltration theory: A paradigm shift in nephrology

Kidney International, 1996
Experimental studies incriminate glomerular hypertension in mediating progressive renal damage after any of a variety of initiating injuries. Prevention of glomerular hypertension by dietary protein restriction or antihypertensive therapy lessens progressive glomerular damage in several experimental models of chronic renal disease.
Elizabeth V. Lawler, Harald S. Mackenzie, Barry M. Brenner   +2 more
openaire   +2 more sources

MRI‐based quantification of whole‐organ renal metabolic rate of oxygen during free‐breathing

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Renal metabolic rate of oxygen (rMRO2) reflects the kidney's metabolic efficiency, making it a potential biomarker for early‐stage kidney disease. This study introduces an ungated, free‐breathing MRI sequence in comparison to its breath‐hold counterpart to noninvasively measure whole‐organ rMRO2.
Nada Kamona, Michael C. Langham, Rajiv S. Deshpande, Brian‐Tinh D. Vu, Mahdie Hosseini, Jeffrey Dennison, Kathryn M. Jaroszynski, Felix W. Wehrli   +7 more
wiley   +1 more source

Fluctuations of estimated glomerular filtration rate outside kidney disease improving global outcomes diagnostic criteria for acute kidney injury in end-stage liver disease outpatients and outcome postliver transplantation [PDF]

, 2017
Background. Renal dysfunction in end-stage liver disease (ESLD) results fromsystemic conditions that affect both liver and kidney with activation of vasoconstrictor systems.
Berloco, Pasquale Bartolomeo, Cappoli, Andrea, Fiacco, Federica, GINANNI CORRADINI, Stefano, Melandro, Fabio, Merli, Manuela, Mitterhofer, Anna Paola, Nofroni, Italo, Poli, Edoardo, Rossi, Massimo, Tinti, Francesca, Umbro, Ilaria, Zavatto, Assunta   +12 more
core   +1 more source

Relative Glomerular Hyperfiltration in Primary Aldosteronism [PDF]

Journal of the American Society of Nephrology, 2005
Experimental and clinical data suggest that primary aldosteronism (PA) may be associated with cardiovascular hypertrophy and fibrosis, in part independent of the BP level. Whether PA may also result in specific deleterious effects on the kidneys was less studied.
Pierre Fesler, Guilhem du Cailar, Albert Mimran, Jean Ribstein   +3 more
openaire   +2 more sources