American Journal of Hematology, Volume 101, Issue 2, Page 304-310, February 2026.ABSTRACT Chronic kidney disease (CKD) is common and a major contributor to increased morbidity and early mortality in people with sickle cell anemia (SCA). Urine albumin‐to‐creatinine ratio (uACR) is recommended to identify patients with SCA‐related CKD but its utility in predicting long‐term kidney dysfunction remains unclear in this patient ...
Pablo Bartolucci +12 more
wiley +1 more source
Renal hyperfiltration and systemic blood pressure in patients with uncomplicated type 1 diabetes mellitus. [PDF]
PLoS ONE, 2013 Patients with type 1 diabetes mellitus (DM) and renal hyperfiltration also exhibit systemic microvascular abnormalities, including endothelial dysfunction. The effect of renal hyperfiltration on systemic blood pressure (BP) is less clear.
Gary K Yang +3 more
doaj +1 more source
Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]
, 2012 Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
core
Age‐Stratified Associations of Sarcopenic Obesity With Mortality in Type 2 Diabetes
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Sarcopenic obesity, the coexistence of sarcopenia and obesity, has been linked to adverse health outcomes due to comorbidity. Evidence on the association between sarcopenic obesity and mortality among individuals with Type 2 diabetes remains limited Methods Sarcopenic obesity was defined using Japan Working Group on Sarcopenic ...
Shinta Yamamoto +16 more
wiley +1 more source
Acta Medica Indonesiana, 2020 Background: living kidney donation is a safe medical procedure. Kidney function after donation is crucial for donors’ health and quality of life. Kidney hyperfiltration is a compensatory mechanism, which will preserve kidney function after unilateral ...
Maruhum Bonar H. Marbun +5 more
doaj +2 more sources
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]
PLoS ONE, 2015 Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman +7 more
doaj +1 more source
Free and total insulin-like growth factor I (IGF-I), IGF-binding protein-1 (IGFBP-1), and IGFBP-3 and their relationships to the presence of diabetic retinopathy and glomerular hyperfiltration in insulin-dependent diabetes mellitus [PDF]
, 1997 The existing literature on serum insulin-like growth factor I (IGF-I) levels in insulin-dependent diabetes mellitus (IDDM) is conflicting. Free IGF-I may have greater physiological and clinical relevance than total IGF-I.
Derkx, F.H.M. (Frans) +5 more
core +4 more sources
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source
Canadian Journal of Kidney Health and Disease, 2023 Background: The use of small pediatric donors (age ≤ 5 years and body weight < 20kg) for adult transplant recipients is still regarded controversially in terms of early complications, long-term outcomes, and development of hyperfiltration injury due to ...
Felix Burkhalter +10 more
doaj +1 more source
Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]
, 2019 Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica +7 more
core +1 more source