Results 231 to 240 of about 74,881 (294)

SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection From Protein Sequences

Aging Cell, Volume 25, Issue 1, January 2026.
We present SenSeqNet, a deep learning framework that predicts cellular senescence directly from protein sequences. SenSeqNet integrates embeddings from the Evolutionary Scale Modeling(ESM‐2) with a hybrid LSTM–CNN architecture to capture both sequential and higher‐order structural features.
Hanli Jiang, Dongliang Deng, Yu Yuan, Jianyu Ren, Xin Yang, Siyi Liu, Bin Tan, Li Lin, Lubin Liu   +8 more
wiley   +1 more source

LncRNA-Associated ceRNA Network in the Spinal Cord Reveals the Central Mechanism of Chronic Inflammatory Visceral Pain. [PDF]

J Pain Res
Li X, Wang X, Dong X, Li Z, Lu Y, Liu L, Yang G, Hong J, Yang Y, Zhang C, Wu H, Zhang D, Ma X.   +12 more
europepmc   +1 more source

Expressions for the generating function of the hypergeometric distributions when the parameters are of different nature

, 1999
Anand P. Singh, H.S. Dhami
openalex   +1 more source

XLVI. The application of solid hypergeometrical series to frequency distributions in space

, 1914
L. Isserlis
openalex   +2 more sources

Single‐Nuclei Resolution of Intermuscular Adipose Tissue Indicates an Inflammation‐Associated Cellular Profile in Individuals With Knee Osteoarthritis: Findings From the SOMMA KOA Ancillary Study

Aging Cell, Volume 25, Issue 1, January 2026.
Interrogation of the cellular and transcriptional profile of IMAT in individuals with KOA reveals a pro‐inflammatory phenotype. ABSTRACT Individuals with knee osteoarthritis (KOA) have skeletal muscle changes around the knee joint including reduced quadricep muscle mass and increased intermuscular adipose tissue (IMAT).
Line O. Elingaard‐Larsen, Katie L. Whytock, Adeline Divoux, Cheehoon Ahn, Giovanna Distefano, Bret H. Goodpaster, Paul M. Coen, Jamie N. Justice, Erin E. Kershaw, Nancy E. Lane, Lauren M. Sparks   +10 more
wiley   +1 more source

ProteinWeaver: A webtool to visualize ontology-annotated protein networks. [PDF]

PLoS One
Anderson O, Barelvi A, O'Brien A, Norman A, Jan I, Ritz A.   +5 more
europepmc   +1 more source

Motor performance and higher associative cortical networks in adolescents with neonatal hypoxic‐ischaemic encephalopathy treated with therapeutic hypothermia

Developmental Medicine &Child Neurology, Volume 68, Issue 1, Page 99-109, January 2026.
Several functional connections between ROIs in the somatomotor (purple) and the default mode network (gray) were significantly associated with the MABC‐2 “aiming and catching” sub‐domain in the HIE cohort in comparison to controls. The colors of the connections represents the correlation coefficient with either negative (light blue to magenta) or ...
Gustaf Håkansson, Mimmi Eriksson Westblad, Maria Örtqvist, Ulrika Ådén, Mats Blennow, Peter Fransson   +5 more
wiley   +1 more source

Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us. [PDF]

PLoS Genet
Wilhelm K, Asmussen J, Lee K, Samieinasab M, Asante E, Kimmel M, Lichtarge O.   +6 more
europepmc   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

The FEBS Journal, Volume 293, Issue 2, Page 396-417, January 2026.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury, Xiaoli Wang, Richard I. Han, Manga Motrapu, Ashley G. Boice, Yuya Nakatani, Sofia Vargas‐Hernandez, Julia F. Love, Claude Chew, Sandra L. Grimm, Dereck Mezquita, Frank M. Mason, Elisabeth D. Martinez, Cristian Coarfa, Cheryl L. Walker, Anna‐Karin Gustavsson, Ruhee Dere   +16 more
wiley   +1 more source

Multi-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum. [PDF]

Nat Commun
Li J, Liao Q, Zhou H, Hu R, Li Y, Hu Z, Yu B, Liu P, Zheng Q, Pu W, Sheng S, Liu Y, Wu S, Liu T, Xiao Q, Duan S, Gao J, Li X, Wang S, Xiao H, Zhou Z, Lu Z, Yang J, Yan J.   +23 more
europepmc   +1 more source