Results 241 to 250 of about 74,881 (294)

STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT The conserved aspartic acid residue D661 within the STAT3 SH2 domain is a recurrent mutational hotspot in hematologic malignancies, including T‐cell large granular lymphocytic leukaemia, myelodysplastic syndromes and acute lymphoblastic leukaemia. To define the functional consequences of distinct STAT3D661 variants, we integrated computational,
Hye Kyung Lee, Gyuhyeok Cho, Jichun Chen, Aaron B. Schultz, Sung‐Gwon Lee, Chengyu Liu, Priscilla A. Furth, Neal S. Young, Jungwook Kim, Alejandro Villarino, Lothar Hennighausen   +10 more
wiley   +1 more source

Level up the brain! Novel PCA method reveals key neuroplastic refinements in action video gamers. [PDF]

Imaging Neurosci (Camb)
Cahill K, Dhamala M.
europepmc   +1 more source

Partial Observability of Implied Volatility Matrices: Identification and Covolatilities Filtering

Mathematical Finance, Volume 36, Issue 1, Page 48-66, January 2026.
ABSTRACT Whereas data on implied volatilities are available for a large number of assets, this is less frequently the case of implied covolatilities. We introduce a new approach based on static and dynamic Wishart models to solve this problem of missing data.
Christian Gouriéroux, Yang Lu
wiley   +1 more source

Genetic regulation of lncRNA expression in whole human brain and their contribution to CNS disorders. [PDF]

Brief Bioinform
He Y, Tang Y, Tan P, Huang D, Wang Y, Wen T, Huang L, Wang J, Shao L, Cai Q, Li Z, Wang Y, Liu T, Han Z.   +13 more
europepmc   +1 more source

Genetic Allee Effects for Controlling Invasive Populations

Molecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Invasive pests threaten food security and devastate ecosystems. A universal problem in their management is that small populations can easily evade detection. This makes identifying new incursions challenging and complicates efforts to eradicate or contain established populations.
Louis Nowell Nicolle, Alex Fournier‐Level, Charles Robin, Ben L. Phillips   +3 more
wiley   +1 more source

Aging reshapes the osteosarcoma ecosystem through immune dysfunction and tumor cell reprogramming. [PDF]

Cell Oncol (Dordr)
Shen R, Chen M, Zhu X, Lin J.
europepmc   +1 more source

Shared and Unique Patterns of Genomic Differentiation and Introgression Between Japanese Stickleback Species Across Three Sympatric Sites

Molecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT Hybridization and introgression frequently occur even between distantly related species. A central question in speciation research is which genomic regions act as barriers to gene flow and how genome‐wide differentiation persists despite hybridization between species.
Genta Okude, Yo Y. Yamasaki, Takuya K. Hosoki, Hiyu Kanbe, Ryo Kakioka, Atsushi J. Nagano, Manabu Kume, Jun Kitano   +7 more
wiley   +1 more source

Highly Recurrent Multinucleotide Mutations in SARS-CoV-2. [PDF]

Mol Biol Evol
De Maio N, Anoufa O, Smith K, Turakhia Y, Goldman N.   +4 more
europepmc   +1 more source

RNA tomography reveals spatial gene expression maps of Arabidopsis thaliana roots infected with Heterodera schachtii

New Phytologist, Volume 249, Issue 1, Page 588-602, January 2026.
Summary Plant‐parasitic cyst nematodes, such as Heterodera schachtii, cause substantial crop losses world‐wide and induce specialized feeding structures in host roots, yet the molecular mechanisms underlying feeding structure initiation and development remain poorly understood.
Anna Pijnacker, Yuhao Wang, Jaap‐Jan Willig, Jonas Mars, Steffen Werner, Kelvin Adema, Geert Smant, Hendrik C. Korswagen, Jose L. Lozano‐Torres   +8 more
wiley   +1 more source