Results 131 to 140 of about 16,683 (210)

SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection From Protein Sequences

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
We present SenSeqNet, a deep learning framework that predicts cellular senescence directly from protein sequences. SenSeqNet integrates embeddings from the Evolutionary Scale Modeling(ESM‐2) with a hybrid LSTM–CNN architecture to capture both sequential and higher‐order structural features.
Hanli Jiang   +8 more
wiley   +1 more source

Motor performance and higher associative cortical networks in adolescents with neonatal hypoxic‐ischaemic encephalopathy treated with therapeutic hypothermia

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 1, Page 99-109, January 2026.
Several functional connections between ROIs in the somatomotor (purple) and the default mode network (gray) were significantly associated with the MABC‐2 “aiming and catching” sub‐domain in the HIE cohort in comparison to controls. The colors of the connections represents the correlation coefficient with either negative (light blue to magenta) or ...
Gustaf Håkansson   +5 more
wiley   +1 more source

Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D. [PDF]

open access: yesNat Commun
Chowdhury B   +18 more
europepmc   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 396-417, January 2026.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury   +16 more
wiley   +1 more source

Partial Observability of Implied Volatility Matrices: Identification and Covolatilities Filtering

open access: yesMathematical Finance, Volume 36, Issue 1, Page 48-66, January 2026.
ABSTRACT Whereas data on implied volatilities are available for a large number of assets, this is less frequently the case of implied covolatilities. We introduce a new approach based on static and dynamic Wishart models to solve this problem of missing data.
Christian Gouriéroux, Yang Lu
wiley   +1 more source

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