Results 21 to 30 of about 16,683 (210)
Advanced Healthcare Materials, EarlyView.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He +4 more
wiley +1 more source
On mini-superspace limit of boundary three-point function in Liouville field theory
, 2017 We study mini-superspace semiclassical limit of the boundary three-point function in the Liouville field theory. We compute also matrix elements for the Morse potential quantum mechanics. An exact agreement between the former and the latter is found.
Apresyan, Elena, Sarkissian, Gor
core +1 more source
Advanced Science, EarlyView.Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li +19 more
wiley +1 more source
A note on moments of derivatives of characteristic polynomials [PDF]
, 2010 We present a simple technique to compute moments of derivatives of unitary characteristic polynomials. The first part of the technique relies on an idea of Bump and Gamburd: it uses orthonormality of Schur functions over unitary groups to compute matrix ...
Dehaye, Paul-Olivier
core
Advanced Science, EarlyView.In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo +19 more
wiley +1 more source
Advanced Science, EarlyView.Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren +9 more
wiley +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Integral representation and sharp asymptotic results for some Heckman-Opdam hypergeometric functions of type BC [PDF]
, 2014 The Heckman-Opdam hypergeometric functions of type BC extend classical Jacobi functions in one variable and include the spherical functions of non-compact Grassmann manifolds over the real, complex or quaternionic numbers.
Rösler, Margit, Voit, Michael
core
On the $b$-functions of hypergeometric systems
, 2017 For any integer $d\times (n+1)$ matrix $A$ and parameter $\beta\in\CC^d$ let $M_A(\beta)$ be the associated $A$-hypergeometric (or GKZ) system in the variables $x_0,\ldots,x_n$. We describe bounds for the (roots of the) $b$-functions of both $M_A(\beta)$
Reichelt, Thomas +2 more
core +1 more source