Results 41 to 50 of about 17,290 (226)

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Recursive Estimation of Orientation Based on the Bingham Distribution [PDF]

, 2013
Directional estimation is a common problem in many tracking applications. Traditional filters such as the Kalman filter perform poorly because they fail to take the periodic nature of the problem into account.
Gilitschenski, Igor, Hanebeck, Uwe D., Julier, Simon, Kurz, Gerhard   +3 more
core  

Commuting difference operators with elliptic coefficients from Baxter's vacuum vestors

, 2000
For quantum integrable models with elliptic R-matrix, we construct the Baxter Q-operator in infinite-dimensional representations of the algebra of observables.Comment: 31 pages, LaTeX, references ...
A Zabrodin, Batchelor M, Baxter R, Baxter R, Bazhanov V, Bazhanov V V, Derkachov S, Derkachov S, Faddeev L D, Faddeev L D, Felder G, Felder G, Felder G, Frenkel I, Gasper G, Korepanov I G, Korepanov I G, Krichever I, Krichever I, Krichever I, Kuznetsov V, Kuznetsov V, Kuznetsov V, Lipatov L N, Pasquier V, Pronko G, Sklyanin E K, Sklyanin E K, Takebe T, Takebe T, Zabrodin A   +30 more
core   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Matrix-Variate Value-at-Risk: Generalized Beta and F Distributions

American Journal of Mathematical and Management Sciences
In recent years, there has been a notable increase in the study of matrix-variate distributions and their applications. Significant progress has been made in understanding the properties and statistical inference of these distributions. In this paper, we
M. Arias-Serna, F. Caro-Lopera, J. Loubes   +2 more
semanticscholar   +1 more source

Evaluating parametric holonomic sequences using rectangular splitting

, 2013
We adapt the rectangular splitting technique of Paterson and Stockmeyer to the problem of evaluating terms in holonomic sequences that depend on a parameter. This approach allows computing the $n$-th term in a recurrent sequence of suitable type using $O(
Johansson, Fredrik
core   +1 more source

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

A note on moments of derivatives of characteristic polynomials [PDF]

, 2010
We present a simple technique to compute moments of derivatives of unitary characteristic polynomials. The first part of the technique relies on an idea of Bump and Gamburd: it uses orthonormality of Schur functions over unitary groups to compute matrix ...
Dehaye, Paul-Olivier
core  

Multivariate hypergeometric functions as tau functions of Toda lattice and Kadomtsev-Petviashvili equation

, 2000
We present the q-deformed multivariate hypergeometric functions related to Schur polynomials as tau-functions of the KP and of the two-dimensional Toda lattice hierarchies.
A.Yu. Orlov, Adler, D.M. Scherbin, Dickey, Dryuma, Gelfand, Gerasimov, Graev, Jimbo, Loutsenko, Mikhailov, Miwa, Morozov, Morozov, Nakatsu, Odzijevicz, Orlov, Segal, Takasaki, Takasaki, Takebe, Ueno, Zakharov, Zakharov   +23 more
core   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source