Results 241 to 250 of about 98,219 (279)

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang   +12 more
wiley   +1 more source

GSH as an A‐A Type Allosteric Activator of PKM2: Modulating Cancer Cell Homeostasis and Ferroptosis Susceptibility

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen   +17 more
wiley   +1 more source

Coordinate‐ and Spacetime‐Independent Quantum Physics

open access: yesAnnalen der Physik, Volume 538, Issue 1, January 2026.
This article studies in the framework of quantum field theory in curved spacetime, if there exists a single zero‐rank‐tensor solution of a Klein‐Gordon PDE, being valid at once for the depicted spacetimes. The answer is shown to be affirmative, even for a class of such solutions having the standard applications in particle physics. ABSTRACT The concept
Viacheslav A. Emelyanov, Daniel Robertz
wiley   +1 more source

Generation of 12 <i>major-terms</i> for interpretating human cellular processes. [PDF]

open access: yesComput Struct Biotechnol J
Liu Y, Liu R, Hu J, Wang Y, Zhang J.
europepmc   +1 more source

Transcriptomic Responses of the Marine Diatom Phaeodactylum tricornutum to High Carbon and Low Nitrogen Stress

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
To elucidate the integrated transcriptional mechanisms underlying diatom acclimation to coupled carbon–nitrogen (CN) imbalance, we employed RNA sequencing (RNA‐Seq) to characterize the global transcriptional response of the model diatom Phaeodactylum tricornutum to high CO2 (~2000 μatm) and low nitrogen (10% of nitrogen concentration in f/2 medium ...
Yi Zhang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy