Results 81 to 90 of about 2,863,909 (272)

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

A Connection Formula for the q-Confluent Hypergeometric Function

Symmetry, Integrability and Geometry: Methods and Applications, 2013
We show a connection formula for the $q$-confluent hypergeometric functions ${}_2varphi_1(a,b;0;q,x)$. Combining our connection formula with Zhang's connection formula for ${}_2varphi_0(a,b;-;q,x)$, we obtain the connection formula for the $q$-confluent ...
Takeshi Morita
doaj   +1 more source

Some integrals of hypergeometric functions [PDF]

, 2017
We consider a certain definite integral involving the product of two classical hypergeometric functions having complicated arguments. We show the surprising fact that this integral does not depend on the parameters of the hypergeometric functions. © 2017,
A. Biró, Biró, András
core   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

A study on unification of generalized hypergeometric function and Mittag-Leffler function with certain integral transforms of generalized basic hypergeometric function

Researches in Mathematics
This research article explores some new properties of generalized hypergeometric function and its q-analogue. The connections between ${}_{2}{{R}_{1}}^{\upsilon }(\mathfrak{z})$, the Wright function, and generalized Mittag-Leffler functions are explored.
K.K. Chaudhary, S.B. Rao
doaj   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Distributions of the Ratio and Product of Two Independent Weibull and Lindley Random Variables

Journal of Probability and Statistics, 2020
In this paper, we derive the cumulative distribution functions (CDF) and probability density functions (PDF) of the ratio and product of two independent Weibull and Lindley random variables.
N. J. Hassan, A. Hawad Nasar, J. Mahdi Hadad   +2 more
doaj   +1 more source

Jacobi elliptic coordinates, functions of Heun and Lame type and the Niven transform [PDF]

, 2005
Lame and Heun functions arise via separation of the Laplace equation in general Jacobi ellipsoidal or conical coordinates. In contrast to hypergeometric functions that also arise via variable separation in the Laplace equation, Lame and Heun functions ...
Kalnins, Ernie G., Miller, W., Jr., W. Miller (Jr), E.G. Kalnins   +3 more
core   +1 more source

Developmentally Guided Differentiation of Ventral Midbrain Dopaminergic Cells Validated in Proteopathy‐Based Parkinson's Disease Models

Advanced Science, EarlyView.
A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon, Heejeong Kim, Elliot H. Lee, Hanseul Kim, Ji Hun Kim, Huisu Jeong, Jiwon Cheon, Ga Ram Jeong, Byoung Dae Lee, Jae‐Won Cho, Soo‐Jin Oh, Yunjong Lee, Yohan Oh   +12 more
wiley   +1 more source

Weighted hypergeometric functions and fractional derivative

Advances in Difference Equations, 2017
We introduce some weighted hypergeometric functions and the suitable generalization of the Caputo fractional derivation. For these hypergeometric functions, some linear and bilinear relations are obtained by means of the mentioned derivation operator ...
JE Restrepo, A Kılıçman, P Agarwal, Omer Altun   +3 more
doaj   +1 more source