Results 221 to 230 of about 38,229 (306)

Deciphering signaling mechanisms and developmental dynamics in extraembryonic mesoderm specification from hESCs. [PDF]

open access: yesNat Commun
Niu B   +14 more
europepmc   +1 more source

Aldehyde Oxidase 1 Deficiency Enhances Aerobic Exercise Performance by Promoting Skeletal Muscle Adaptation and Improving Mitochondrial Function

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Aox1 expression is negatively associated with the oxidative muscle fiber phenotype and is downregulated by endurance training. Aox1 deficiency enhances aerobic exercise capacity in mice, at least in part, through the upregulation of PGC‐1α, which promotes oxidative fiber‐type transition, boosts mitochondrial oxidative phosphorylation, and increases ...
Yan Liu   +10 more
wiley   +1 more source

Single‐Cell RNA Sequencing Highlights a Contribution of Human Amniotic Mesenchymal Stem Cells‐Derived Exosomes to Androgenetic Alopecia

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
hAMSC‐exo inhibited DPC damage by ameliorating DHT‐induced mitochondrial dysfunction in dependence on Wnt/β‐catenin signaling, and then potentially strengthened crosstalk between DPC and cycling HF cells, which was vital for appropriately regulating HFSC activity to initiate hair growth.
Xiao‐Yu Wang   +7 more
wiley   +1 more source

dbscATAC: a resource of single-cell super-enhancers/enhancers and gene markers derived from scATAC-seq data. [PDF]

open access: yesBioinformatics
Li Y   +13 more
europepmc   +1 more source

Obesity Affects IVF Outcomes and Mevalonic Acid Rescues the Side Effects of Statins on Follicle Growth

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Obesity reduces in vitro fertilization pregnancy success, with significant decreases in the number of retrieved oocytes, mature oocytes, and cleavage embryos. Mevalonic acid rescues potential productive toxicity of the lipid‐lowering drug simvastatin in follicular development.
Fei Mao   +8 more
wiley   +1 more source

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 7, Page 1454-1464, July 2025.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy