Results 221 to 230 of about 38,611 (276)

Reduced Proteasome Degradation of HSF‐1 Shifts Protein Stress Management With Age in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 2, February 2026.
Ageing C. elegans prioritises chronic protein stress protection over acute stress response by coordinating HSF‐1 activity. Decreased PBS‐7 binding in aged worms reduces HSF‐1 degradation, enhancing its ability to upregulate protective factors against accumulating protein aggregates while simultaneously suppressing its activation under acute heat shock.
Hongwei Wang, Fengzhen Sun, Zhidong He, Xiaojie Wang, Hao Liu, Mengjiao Song, Qingxia Chen, Zhixue Li, Ligang Wu, Xiumin Yan, Xueliang Zhu, Yidong Shen   +11 more
wiley   +1 more source

The poplar pathogen <i>Sphaerulina musiva</i> has a dynamic genome architecture marked by chromosomal inversions and changes in transposable element abundance. [PDF]

Microb Genom
Zaccaron AZ, Lassagne A, Søndreli KL, Sudermann MA, Alcalá Briseño RI, Grünwald NJ, Weisberg AJ, LeBoldus JM.   +7 more
europepmc   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source

Highest-Weight Vectors and Three-Point Functions in GKO Coset Decomposition. [PDF]

Commun Math Phys
Bershtein M, Feigin B, Trufanov A.
europepmc   +1 more source

Lycium barbarum polysaccharides enhance testicular spermatogenesis in d‐galactose‐induced aging rats via calcium signaling

Andrology, Volume 14, Issue 2, Page 496-515, February 2026.
Abstract Background Lycium barbarum polysaccharide (LBP) has long been recognized as having a wide range of beneficial properties for improving proliferation. However, the protective effects and specific mechanisms of d‐galactose‐induced testicular dysfunction in reproductively senescent rats are not fully understood.
Wenxin Ma, Chang Liu, Jing Pu, Ziyu Liu, Na Hu, Li Yang, Dongmei Chen, Hongmei Li, HuiMing Ma   +8 more
wiley   +1 more source

A Review: Construction of Statistical Distributions. [PDF]

Entropy (Basel)
Fang KT, Lin YX, Deng YH.
europepmc   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source

METTL3 safeguards cell identity and epigenome of human trophoblast stem cells. [PDF]

Nat Commun
Fu H, Chen C, Huang Y, Zhang W, Li S, Chan FF, Xu L, Ruan D, Ouyang X, Ma L, Feng Z, Zhang Q, Wang C, Heng D, Yao K, Javed A, Wong CM, Lee YL, Yeung WSB, Sun B, Liu P.   +20 more
europepmc   +1 more source

Effects of Seating Arrangements on Parliamentary Collaborations

Legislative Studies Quarterly, Volume 51, Issue 1, February 2026.
ABSTRACT Does parliamentary seating affect parliamentary behavior? In this paper, we dig into the question of whether spatial proximity affects the behavior of elected representatives. Using data from the 50th legislative period of the Swiss parliament and an inferential network model, we estimate the effects of different operationalizations of seating
Laurence Brandenberger, Teodora Bujaroska   +1 more
wiley   +1 more source

Study analytical function subordination properties by applying a novel linear operator. [PDF]

F1000Res
Majel MS, Hameed MI.
europepmc   +1 more source