Results 71 to 80 of about 38,611 (276)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

The Kummer confluent hypergeometric function and some of its applications in the theory of azimuthally magnetized circular ferrite waveguides

open access: yesJournal of Telecommunications and Information Technology, 2005
Examples of the application of the confluent hypergeometric functions in miscellaneous areas of the theoretical physics are presented. It is suggested these functions to be utilized as a universal means for solution of a large number of problems ...
Georgi Nikolov Georgiev   +1 more
doaj   +1 more source

A simple proof of Bailey's very-well-poised 6-psi-6 summation

open access: yes, 2000
We give elementary derivations of some classical summation formulae for bilateral (basic) hypergeometric series. In particular, we apply Gauss' 2-F-1 summation and elementary series manipulations to give a simple proof of Dougall's 2-H-2 summation ...
Schlosser, M.
core   +1 more source

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

open access: yesAdvanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng   +27 more
wiley   +1 more source

Elementary derivations of identities for bilateral basic hypergeometric series

open access: yes, 2000
We give elementary derivations of several classical and some new summation and transformation formulae for bilateral basic hypergeometric series. For purpose of motivation, we review our previous simple proof ("A simple proof of Bailey's very-well-poised
Schlosser, M.
core   +1 more source

Legendre inversions and balanced hypergeometric series identities

open access: yesDiscrete Mathematics, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
CHU, Wenchang, WEI C.
openaire   +2 more sources

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou   +13 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Modular forms, Schwarzian conditions, and symmetries of differential equations in physics

open access: yes, 2017
We give examples of infinite order rational transformations that leave linear differential equations covariant. These examples are non-trivial yet simple enough illustrations of exact representations of the renormalization group.
Abdelaziz, Y., Maillard, J. -M.
core   +3 more sources

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