Results 31 to 40 of about 72,161 (124)

Pharmacovigilance Signal Detection and Mutually Exclusive Driver Mutations of the PI3K/AKT Pathway in Breast Cancer Treated With Capivasertib

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Background and Objective This study is aimed at comprehensively evaluating the real‐world safety profile and underlying molecular mechanisms of the AKT inhibitor capivasertib by integrating pharmacovigilance data, computational biology, and multiomics analyses.
Zhanyang Luo   +7 more
wiley   +1 more source

Ventricular septal rupture presenting with hyperosmolar hyperglycemic nonketotic coma

open access: yesSaudi Medical Journal, 2007
[Abstract Not Available]
Tatli, Ersan   +3 more
openaire   +3 more sources

Is Insulin Resistance the Driver or the Outcome of Diabetes Mellitus? A Critical Review

open access: yesJournal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Insulin resistance (IR) and Type 2 diabetes mellitus (DM) are intricately related metabolic conditions that significantly contribute to the global health burden. IR is characterized by chronic hyperglycemia that triggers a cascade of metabolic dysfunctions, including alterations in insulin signaling and the promotion of IR via inflammatory pathways ...
Shafa Shahid   +6 more
wiley   +1 more source

Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications

open access: yesJournal of Diabetes Research, Volume 2018, Issue 1, 2018., 2018
High morbidity and mortality of diabetes mellitus (DM) throughout the human population is a serious threat which needs to be addressed cautiously. Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are most prevalent forms. Disruption in insulin regulation and resistance leads to increased formation and accumulation of advanced end ...
Bou-Yue Peng   +7 more
wiley   +1 more source

Hyperglycemic Hyperosmolar State: A Diabetic Emergency [PDF]

open access: yes, 2015
Hyperglycemic hyperosmolar state (HHS) is an acute complication associated with diabetes mellitus. HHS has been known by several other names in the past.
Fisher, Rachel
core  

Retrospective Evaluation of Prognostic Variables and Overall Survival Associated With Nonketotic Hyperosmolar Hyperglycemia in Diabetic Cats: 29 Cases (2000–2020)

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 35, Issue 4, Page 415-424, July/August 2025.
ABSTRACT Objective To compare survival between cats diagnosed with a nonketotic hyperosmolar hyperglycemic state (HHS) and cats diagnosed with diabetic ketoacidosis (DKA), and to determine whether clinical parameters, clinicopathologic data, and insulin type are associated with survival.
Annalisa Judy, Aaron Rendahl, Kelly Tart
wiley   +1 more source

Nonketotic hyperosmolar coma in a patient with type 1 diabetes-related diabetic nephropathy: Case report

open access: yes, 2005
Nonketotic hyperosmolar coma (NHC) is characterized by severe hyperglycemia; absence of, or only slight ketosis; nonketotic acidosis; severe dehydration; depressed sensorium or frank coma; and various neurologic signs.
Buyukbese, A   +3 more
core   +1 more source

An analysis of the impact on total cost of care within a pharmacist‐led comprehensive medication management program

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 10, Page 984-995, October 2024.
Abstract Introduction The rise in health care expenditures continues to pose a significant concern regarding the longevity of the current health care system design. The literature has demonstrated a positive return on investment (ROI) when pharmacists perform medication management services. Building upon positive ROI literature, a clinically integrated
Julie Anne Earby   +4 more
wiley   +1 more source

PATHOGENESIS OF NONKETOTIC HYPEROSMOLAR DIABETIC COMA

open access: yes, 1975
Two concepts are advanced to explain some of the puzzling biochemical features found in nonketotic hyperosmolar diabetic coma. It is firstly suggested that an insulinised liver (reflecting residual beta-cell secretory activity) coexists with a diabetic ...
Joffe, B.I   +3 more
core   +1 more source

Acute stroke-like deficits associated with nonketotic hyperglycemic hyperosmolar state: an illustrative case and systematic review of literature [PDF]

open access: yes, 2022
INTRODUCTION: Nonketotic hyperglycemic hyperosmolar state (NKHHS) is associated with a wide spectrum of neurological syndromes including acute stroke-like deficits. Clinical features and etiology have not been established yet.
Querzani, Pietro   +20 more
core   +1 more source

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