Results 31 to 40 of about 72,161 (124)
Background and Objective This study is aimed at comprehensively evaluating the real‐world safety profile and underlying molecular mechanisms of the AKT inhibitor capivasertib by integrating pharmacovigilance data, computational biology, and multiomics analyses.
Zhanyang Luo +7 more
wiley +1 more source
Ventricular septal rupture presenting with hyperosmolar hyperglycemic nonketotic coma
[Abstract Not Available]
Tatli, Ersan +3 more
openaire +3 more sources
Is Insulin Resistance the Driver or the Outcome of Diabetes Mellitus? A Critical Review
Insulin resistance (IR) and Type 2 diabetes mellitus (DM) are intricately related metabolic conditions that significantly contribute to the global health burden. IR is characterized by chronic hyperglycemia that triggers a cascade of metabolic dysfunctions, including alterations in insulin signaling and the promotion of IR via inflammatory pathways ...
Shafa Shahid +6 more
wiley +1 more source
Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications
High morbidity and mortality of diabetes mellitus (DM) throughout the human population is a serious threat which needs to be addressed cautiously. Type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are most prevalent forms. Disruption in insulin regulation and resistance leads to increased formation and accumulation of advanced end ...
Bou-Yue Peng +7 more
wiley +1 more source
Hyperglycemic Hyperosmolar State: A Diabetic Emergency [PDF]
Hyperglycemic hyperosmolar state (HHS) is an acute complication associated with diabetes mellitus. HHS has been known by several other names in the past.
Fisher, Rachel
core
ABSTRACT Objective To compare survival between cats diagnosed with a nonketotic hyperosmolar hyperglycemic state (HHS) and cats diagnosed with diabetic ketoacidosis (DKA), and to determine whether clinical parameters, clinicopathologic data, and insulin type are associated with survival.
Annalisa Judy, Aaron Rendahl, Kelly Tart
wiley +1 more source
Nonketotic hyperosmolar coma (NHC) is characterized by severe hyperglycemia; absence of, or only slight ketosis; nonketotic acidosis; severe dehydration; depressed sensorium or frank coma; and various neurologic signs.
Buyukbese, A +3 more
core +1 more source
Abstract Introduction The rise in health care expenditures continues to pose a significant concern regarding the longevity of the current health care system design. The literature has demonstrated a positive return on investment (ROI) when pharmacists perform medication management services. Building upon positive ROI literature, a clinically integrated
Julie Anne Earby +4 more
wiley +1 more source
PATHOGENESIS OF NONKETOTIC HYPEROSMOLAR DIABETIC COMA
Two concepts are advanced to explain some of the puzzling biochemical features found in nonketotic hyperosmolar diabetic coma. It is firstly suggested that an insulinised liver (reflecting residual beta-cell secretory activity) coexists with a diabetic ...
Joffe, B.I +3 more
core +1 more source
Acute stroke-like deficits associated with nonketotic hyperglycemic hyperosmolar state: an illustrative case and systematic review of literature [PDF]
INTRODUCTION: Nonketotic hyperglycemic hyperosmolar state (NKHHS) is associated with a wide spectrum of neurological syndromes including acute stroke-like deficits. Clinical features and etiology have not been established yet.
Querzani, Pietro +20 more
core +1 more source

