Results 71 to 80 of about 11,659 (226)

Robotic Bilateral Sympathectomy for Hyperhidrosis

, 2020
Hyperhidrosis is a relatively common disorder which produces a lot of unhappiness and psychological stress to otherwise healthy individuals. Patients suffer from excessive sweating of the underarms (axillary hyperhidrosis) or of the palms and soles of ...
Dimitrios Kyparissopoulos (8379543)
core   +1 more source

The epidemiological and clinical association between primary focal hyperhidrosis and various skin disease in Japanese patients: outpatient questionnaire analysis

Journal of Cutaneous Immunology and Allergy
Hyperhidrosis, defined as excessive sweating beyond physiological needs. It impairs the quality of life (QOL) of patients. While there are many studies on the relationship between sweating and skin diseases, however few studies have been conducted from ...
Keiji Kosaka, Akihiko Uchiyama, Mai Ishikawa, Sei-Ichiro Motegi   +3 more
doaj   +1 more source

A retrospective review on minimally invasive technique via endoscopic thoracic sympathectomy (ETS) in the treatment of severe primary hyperhidrosis: Experiences from the National Heart Institute, Malaysia [version 1; peer review: 2 approved]

F1000Research, 2018
Background: Hyperhidrosis is due to the hyperactive autonomic stimulation of the sweat glands in response to stress. Primary hyperhidrosis is a common yet psychologically disabling condition.
Ahmad Farouk Musa, Vignaa Prashanth Gandhi, Jeswant Dillon, Rusli Bin Nordin   +3 more
doaj   +1 more source

Cutaneous Adverse Drug Reactions Associated With BRAF and MEK Inhibitors: A Real‐World Analysis of WHO Pharmacovigilance Data

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 274-285, July 2026.
BRAF inhibitors and MEK inhibitors (MEKi) have reshaped the treatment of BRAFV600‐mutant malignancies; however, cutaneous adverse drug reactions (ADRs) remain a frequent and clinically impactful toxicity. Although clinical trials provide insight into their safety profiles, real‐world data on dermatologic ADRs are limited.
Natalia Sauer, Piotr Giedziun, Jacek Calik, Anna Wiela‐Hojeńska   +3 more
wiley   +1 more source

Hyperhidrosis: Causes and treatments

, 2014
Sweating helps to regulate body temperature by cooling via the evaporation of sweat produced by sweat glands. Hyperhidrosis is a condition characterized by constant and increased production of sweat by sweat glands, and may be local (primary) or ...
Takase, Luiz Fernando, Nogueira, Camila Tita [UNESP], Rodella, Patrícia [UNESP], Urbaczek, Ana Carolina   +3 more
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Tri‐Parametric Assessment of α‐Galactosidase A Activity, lysoGb3 and X‐Inactivation Aids Genotype‐Phenotype Categorization of Fabry Disease Female Patients

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Fabry disease (FD, OMIM 301500) is an X‐linked lysosomal storage disorder caused by deficient activity of lysosomal alpha‐galactosidase A (AGAL, E.C. 3.2.1.22) due to pathogenic variants in the GLA gene (HGNC:4296, Xq22.1). Plasmatic deacylated globotriaosylceramide (lysoGb3) is elevated in FD patients as a reflection of lysosomal accumulation
Ladislav Kuchar, Lenka Dvorakova, Linda Berna, Martin Reboun, Petra Slavikova, Radovan Bakalar, Jana Ledvinova, Helena Poupetova, Petr Ruzicka, Asfaw Befekadu, Gabriela Dostalova, Stella Reichmannova, Ales Linhart, Jakub Sikora   +13 more
wiley   +1 more source

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva, Joseph Youkilis, Yogith Rao, Alex Straiker   +3 more
wiley   +1 more source

Comparative study of transepidermal water loss in patients with and without hyperhidrosis by closed-chamber measurer in an air-conditioned environment

Einstein (São Paulo)
Objective To evaluate the difference in transepidermal water loss in patients diagnosed with hyperhidrosis and healthy subjects, in an air-conditioned environment.
Andre Miotto, Pedro Augusto Antunes Honda, Thiago Gangi Bachichi, Caio Santos Holanda, Ernesto Evangelista Neto, João Alessio Juliano Perfeito, Luiz Eduardo Villaça Leão, Altair da Silva Costa Jr   +7 more
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, Volume 13, Issue 33, 15 June 2026.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Genetic polymorphism analysis of patients with primary hyperhidrosis

, 2018
Bryce C Simes,1 Joshua P Moore,1 Terry C Brown,1 Tyler J Rushforth,1 Angela L Bookout,2 Chante L Richardson1 1Alabama College of Osteopathic Medicine, Dothan, AL, USA; 2Southern Institute of Dermatology, Dothan, AL, USA Background: Hyperhidrosis affects ...
Brown TC, Richardson CL, Simes BC, Moore JP, Bookout AL, Rushforth TJ   +5 more
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