Results 71 to 80 of about 16,858 (213)

Hyperhidrosis

TURKDERM, 2011
Hyperhidrosis, which affects nearly 3% of the population, is characterized by excessive sweating due to eccrine sweat gland hyperactivity. It has negative impact on quality of life, and social relations and also may lead to social anxiety disorders.
Onder, Meltem, Aksoy, Gulhan
openaire   +3 more sources

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 790-799, April 2026.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

The epidemiological and clinical association between primary focal hyperhidrosis and various skin disease in Japanese patients: outpatient questionnaire analysis

Journal of Cutaneous Immunology and Allergy
Hyperhidrosis, defined as excessive sweating beyond physiological needs. It impairs the quality of life (QOL) of patients. While there are many studies on the relationship between sweating and skin diseases, however few studies have been conducted from ...
Keiji Kosaka, Akihiko Uchiyama, Mai Ishikawa, Sei-Ichiro Motegi   +3 more
doaj   +1 more source

Phase II Trial of Opaganib Addition in Metastatic Castration‐Resistant Prostate Cancer After Disease Progression on Abiraterone or Enzalutamide

Cancer Medicine, Volume 15, Issue 4, April 2026.
This phase II trial investigated the safety and efficacy of opaganib in combination with abiraterone or enzalutamide in patients with castration‐resistant prostate cancer (CRPC). While the study did not meet its disease control efficacy endpoint, there was evidence of clinical activity in a subset of patients.
Jacqueline T. Brown, Bassel Nazha, Anna C. Ferreira, Kent Armeson, Elizabeth G. Hill, Besim Ogretmen, Shikhar Mehrotra, Alan Brisendine, George Magrath, Terry F. Plasse, Theodore Stewart Gourdin, Omer Kucuk, Michael Lilly   +12 more
wiley   +1 more source

A retrospective review on minimally invasive technique via endoscopic thoracic sympathectomy (ETS) in the treatment of severe primary hyperhidrosis: Experiences from the National Heart Institute, Malaysia [version 1; peer review: 2 approved]

F1000Research, 2018
Background: Hyperhidrosis is due to the hyperactive autonomic stimulation of the sweat glands in response to stress. Primary hyperhidrosis is a common yet psychologically disabling condition.
Ahmad Farouk Musa, Vignaa Prashanth Gandhi, Jeswant Dillon, Rusli Bin Nordin   +3 more
doaj   +1 more source

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno, Nancy Muriel Herrera Leaño, María Juliana Soto Chávez, Darío Parra Prieto, Alejandro Mariño Correa   +4 more
wiley   +1 more source

Outpatient alcohol detoxification: Implementation efficacy and outcome effectiveness of a model project [PDF]

, 2004
Background: The aim of the study was to examine the practicability and implementation efficacy of an alcohol outpatient detoxification model and the concomitant `motivational' psychotherapeutic approach.
Horak, M., Soyka, Michael
core   +1 more source

Inverse Pityriasis Versicolor (PV)

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Inverse pityriasis versicolor (PV) involving the groin and scrotum is an uncommon presentation of PV. Despite its uncommon location, PV should be suspected in patients with scaly and persistent hypo or hyperpigmented lesions, especially in regions with hot and humid environment. Early recognition allows effective antifungal therapy, preventing
Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane, Aditi Joshi   +4 more
wiley   +1 more source

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study

Epilepsia, Volume 67, Issue 4, Page 1703-1721, April 2026.
Abstract Objective CDKL5 deficiency disorder (CDD) is a rare X‐linked developmental and epileptic encephalopathy caused by loss‐of‐function variants in the CDKL5 gene. Preclinical experiments using enzyme replacement or gene therapies show promise and could be transformative therapies.
Xavier Liogier d'Ardhuy, CANDID Partners, Tricia Cimms, Kristina Lindsten, Marco Rizzo, Alison Skrinar, Peter St. Wecker, Ana Mingorance, Orrin Devinsky   +8 more
wiley   +1 more source

Comparative study of transepidermal water loss in patients with and without hyperhidrosis by closed-chamber measurer in an air-conditioned environment

Einstein (São Paulo)
Objective To evaluate the difference in transepidermal water loss in patients diagnosed with hyperhidrosis and healthy subjects, in an air-conditioned environment.
Andre Miotto, Pedro Augusto Antunes Honda, Thiago Gangi Bachichi, Caio Santos Holanda, Ernesto Evangelista Neto, João Alessio Juliano Perfeito, Luiz Eduardo Villaça Leão, Altair da Silva Costa Jr   +7 more
doaj   +1 more source