Results 141 to 150 of about 12,970 (183)
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Hyperhomocysteinemia and thrombosis
Lipids, 2001AbstractHomocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of methionine, which is dependent on vitamins (folic acid, B12, and B6) as cofactors or cosubstrates. In 1969, McCully first reported the presence of severe atherosclerotic lesions in patients with severe hyperhomocysteinemia and hypothesized the existence of a ...
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Diabetes Mellitus and Hyperhomocysteinemia
Seminars in Vascular Medicine, 2002Patients with diabetes mellitus are prone to cardiovascular disease and risk factors presumably unrelated to diabetes, such as hyperhomocysteinemia, may be involved in the atherothrombotic process in these subjects. Plasma homocysteine levels are usually normal in diabetes, although both lower and higher levels have been reported.
Coen, van Guldener, Coen D A, Stehouwer
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2006
Abstract A 35-year-old man presented to his family physician after he noted a 20-min episode of slurred speech and weakness of his left arm. He had had a similar episode, lasting 10 min, 3 days earlier. He had never smoked cigarettes, and he had no history of high blood pressure, high cholesterol, diabetes, stroke, or neurological ...
Angela M Devlin, Steven R Lentz
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Abstract A 35-year-old man presented to his family physician after he noted a 20-min episode of slurred speech and weakness of his left arm. He had had a similar episode, lasting 10 min, 3 days earlier. He had never smoked cigarettes, and he had no history of high blood pressure, high cholesterol, diabetes, stroke, or neurological ...
Angela M Devlin, Steven R Lentz
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Genetic Basis of Hyperhomocysteinemia
Molecular Genetics and Metabolism, 2000Homocysteine is a sulfur-containing, nonproteinogenic amino acid biosynthesized from methionine which has a key place in common between the folate cycle and the activated methyl cycle. Homocysteine export into the extracellular medium reflects an imbalance between homocysteine production and metabolism (1). Hyperhomocysteinemia has been associated with
M A, Medina, M I, Amores-Sánchez
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Hyperhomocysteinemia and Venous Thrombosis
Seminars in Hematology, 2007It has been recognized, since the first description of the disease, that arterial and venous thrombosis are common in patients with homocysteinuria. Interest in the condition increased with reports from a large number of mainly retrospective studies showing that mildly elevated homocysteine levels are also associated with venous thromboembolism (VTE ...
Alex, Gatt, Michael, Makris
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Hyperhomocysteinemia and Arterial Aneurysm
Annals of Vascular Surgery, 2002Hyperhomocysteinemia (HCY) is an independent risk factor for atherosclerosis. Arterial aneurysm has rarely been described in association with heterozygous HCY. Here we report two cases of this association. Case 1 was 32-Year-old man who presented with distal trophic manifestations of the lower extremities. Upon investigation, occlusive arterial disease
P, Cacoub +6 more
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Hyperhomocysteinemia and Venous Thromboembolism
Seminars in Thrombosis and Hemostasis, 2006Homocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of methionine, which is dependent on vitamins (folic acid, B12 and B6) as cofactors or cosubstrates. Severe hyperhomocysteinemia (homocystinuria), due to inherited metabolic defects of Hcy metabolism, is associated with very high risk of venous thromboembolism (VTE ...
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Hyperhomocysteinemia, Atherosclerosis and Thrombosis
Thrombosis and Haemostasis, 1999SummaryHigh plasma levels of homocysteine are the results of the interplay between congenital and environmental factors. In the last two decades, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor of thromboembolic diseases.
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Hyperhomocysteinemia and Immune Activation
Clinical Chemistry and Laboratory Medicine, 2003Hyperhomocysteinemia is an established risk factor for atherosclerosis, thrombosis and other vascular diseases. Homocysteine auto-oxidation is considered to be crucially involved in the pathogenesis of these diseases. However, the question remains to be elucidated whether vitamin deficiency and homocysteine accumulation are causal for disease ...
Katharina, Schroecksnadel +5 more
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Hyperhomocysteinemia, inflammation and autoimmunity
Autoimmunity Reviews, 2007Hyperhomocysteinemia is independently associated with the development of coronary, cerebral and peripheral vascular disease and deep-vein thrombosis in the general population. The evidence that cardiovascular involvement is particularly frequent and advanced in patients affected with several autoimmune diseases (AD), in which hyperhomocysteinemia ...
Lazzerini, P. E. +6 more
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