Results 141 to 150 of about 13,048 (184)

Diabetes Mellitus and Hyperhomocysteinemia

Seminars in Vascular Medicine, 2002
Patients with diabetes mellitus are prone to cardiovascular disease and risk factors presumably unrelated to diabetes, such as hyperhomocysteinemia, may be involved in the atherothrombotic process in these subjects. Plasma homocysteine levels are usually normal in diabetes, although both lower and higher levels have been reported.
Coen, van Guldener, Coen D A, Stehouwer
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Genetic Basis of Hyperhomocysteinemia

Molecular Genetics and Metabolism, 2000
Homocysteine is a sulfur-containing, nonproteinogenic amino acid biosynthesized from methionine which has a key place in common between the folate cycle and the activated methyl cycle. Homocysteine export into the extracellular medium reflects an imbalance between homocysteine production and metabolism (1). Hyperhomocysteinemia has been associated with
M A, Medina, M I, Amores-Sánchez
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Hyperhomocysteinemia and Venous Thrombosis

Seminars in Hematology, 2007
It has been recognized, since the first description of the disease, that arterial and venous thrombosis are common in patients with homocysteinuria. Interest in the condition increased with reports from a large number of mainly retrospective studies showing that mildly elevated homocysteine levels are also associated with venous thromboembolism (VTE ...
Alex, Gatt, Michael, Makris
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Hyperhomocysteinemia and Immune Activation

Clinical Chemistry and Laboratory Medicine, 2003
Hyperhomocysteinemia is an established risk factor for atherosclerosis, thrombosis and other vascular diseases. Homocysteine auto-oxidation is considered to be crucially involved in the pathogenesis of these diseases. However, the question remains to be elucidated whether vitamin deficiency and homocysteine accumulation are causal for disease ...
Katharina, Schroecksnadel, Barbara, Frick, Christiana, Winkler, Friedrich, Leblhuber, Barbara, Wirleitner, Dietmar, Fuchs   +5 more
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Hyperhomocysteinemia and Venous Thromboembolism

Seminars in Thrombosis and Hemostasis, 2006
Homocysteine (Hcy) is a sulfhydryl amino acid derived from the metabolic conversion of methionine, which is dependent on vitamins (folic acid, B12 and B6) as cofactors or cosubstrates. Severe hyperhomocysteinemia (homocystinuria), due to inherited metabolic defects of Hcy metabolism, is associated with very high risk of venous thromboembolism (VTE ...
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Hyperhomocysteinemia and Arterial Aneurysm

Annals of Vascular Surgery, 2002
Hyperhomocysteinemia (HCY) is an independent risk factor for atherosclerosis. Arterial aneurysm has rarely been described in association with heterozygous HCY. Here we report two cases of this association. Case 1 was 32-Year-old man who presented with distal trophic manifestations of the lower extremities. Upon investigation, occlusive arterial disease
P, Cacoub, A, Sbai, I, Brocheriou, E, Kaloustian, G, Cohen, E, Kieffer, J C, Piette   +6 more
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Hyperhomocysteinemia, Atherosclerosis and Thrombosis

Thrombosis and Haemostasis, 1999
SummaryHigh plasma levels of homocysteine are the results of the interplay between congenital and environmental factors. In the last two decades, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor of thromboembolic diseases.
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Hyperhomocysteinemia, inflammation and autoimmunity

Autoimmunity Reviews, 2007
Hyperhomocysteinemia is independently associated with the development of coronary, cerebral and peripheral vascular disease and deep-vein thrombosis in the general population. The evidence that cardiovascular involvement is particularly frequent and advanced in patients affected with several autoimmune diseases (AD), in which hyperhomocysteinemia ...
Lazzerini, P. E., Capecchi, P. L., Selvi, E., Lorenzini, S., Bisogno, S., Galeazzi, Mauro, Laghi Pasini, Franco   +6 more
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Hyperhomocysteinemia and Venous Thrombosis

The International Journal of Lower Extremity Wounds, 2002
Deep vein thrombosis (DVT) leads to venous ulcers in later life. Venous ulcers are the majority of chronic lower extremity wounds. Recent evidence suggests that hyperhomocysteinemia is an independent risk factor for venous thrombosis. Other evidence suggests that dietary supplementation with folic acids and vitamins helps to change hyper ...
Paul, Lee, Kailash, Prasad
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Hyperhomocysteinemia and Atherothrombotic Disease

Seminars in Thrombosis and Hemostasis, 1998
Hyperhomocysteinemia is an independent risk factor for atherothrombotic disease. The mechanism by which homocysteine induces atherosclerosis and thrombosis is not fully understood. Data on arterial histology in humans with homocystinuria and mild hyperhomocysteinemia are limited.
S C, de Jong, M, van den Berg, J A, Rauwerda, C D, Stehouwer   +3 more
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