Results 51 to 60 of about 41,059 (214)

Aliskiren, enalapril, or aliskiren and enalapril in heart failure [PDF]

, 2016
BACKGROUND Among patients with chronic heart failure, angiotensin-converting–enzyme (ACE) inhibitors reduce mortality and hospitalization, but the role of a renin inhibitor in such patients is unknown.
], Akshay S. Desai, Barry M. Massie, Claudio Borghi, for the ATMOSPHERE Committees Investigators [, Georgia Tarnesby, Henry Krum, John J.V. McMurray, Kenneth Dickstein, Lars V. Køber, M. Atif Ali, Nicola Greenlaw, Qing Shao, Scott D. Solomon, William T. Abraham, Yanntong Chiang   +15 more
core   +5 more sources

Investigating the efficacy of mineralocorticoid receptor antagonists for cardiovascular outcomes in different diseases

ESC Heart Failure, EarlyView.
Abstract Aims Mineralocorticoid receptor antagonists (MRAs) are crucial in managing cardiovascular diseases, with different MRAs demonstrating varying efficacy across diverse disease contexts. This research aims to compare the cardiovascular protective effects of different MRAs across various disease conditions.
Jiao Wang, Meijuan Zheng, Yuchun Yang, Lei Zhang, Muhuyati Wulasihan   +4 more
wiley   +1 more source

Efficacy and safety of sodium zirconium cyclosilicate in patients with baseline serum potassium level ≥ 5.5 mmol/L: pooled analysis from two phase 3 trials. [PDF]

, 2019
BackgroundReliable, timely-onset, oral treatments with an acceptable safety profile for patients with hyperkalemia are needed. We examined the efficacy and safety of sodium zirconium cyclosilicate (SZC; formerly ZS-9) treatment for ≤ 48 h in patients ...
Amin, Alpesh N, Kim, Christopher S, Menoyo, Jose, Singh, Bhupinder   +3 more
core  

Incidence of Co-Trimoxazole-Induced Hyperkalemia in a Tertiary Care Hospital

Risk Management and Healthcare Policy, 2021
Rana M Al AdAwi1 1, Zainab Albu-Mahmood1 1, Mohamed Abdelgelil1 1, Hani Abdelaziz,2 Derek Stewart3 3, Ahmed Awaisu3 1Clinical Pharmacist, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; 2Clinical Pharmacist Supervisor, Al Wakra Hospital ...
Al AdAwi RM, Albu-Mahmood Z, Abdelgelil M, Abdelaziz H, Stewart D, Awaisu A   +5 more
doaj  

Histopathological Features of the Testes of a Patient With Congenital Lipoid Adrenal Hyperplasia

IJU Case Reports, EarlyView.
ABSTRACT Introduction Congenital lipoid adrenal hyperplasia (CLAH) is a type of congenital adrenal hyperplasia characterized by reduced steroid production. Patients with this endocrine disorder as well as chromosome 46,XY have testes and female external genitalia. Because these individuals are usually raised as female, the testes are removed.
Takuya Sakata, Kentaro Mizuno, Daisuke Matsumoto, Hidenori Nishio, Atsushi Suzuki, Kohei Aoyama, Atsushi Ishida, Takahiro Yasui, Haruo Mizuno, Yutaro Hayashi   +9 more
wiley   +1 more source

Operative and nonoperative management of acute cholecystitis in patients on chronic kidney replacement therapy

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Patients with kidney failure receiving chronic kidney replacement therapy (KRT: dialysis or kidney transplantation) have increased risks of postoperative mortality and morbidity. This study assesses the outcomes of acute cholecystitis in patients on chronic KRT who undergo cholecystectomy compared to nonoperative management ...
Dharmenaan Palamuthusingam, Carmel M. Hawley, Elaine M. Pascoe, David Wayne Johnson, Palvannan Sivalingam, Simon T. Wood, Pranavan Palamuthusingam, Matthew D. Jose, Magid Fahim   +8 more
wiley   +1 more source

Electrolyte Abnormalities on ECG [PDF]

, 2011
The authors review the characteristic changes that hypercalcemia, hyperkalemia, hypokalemia, and other serum electrolyte abnormalities can cause on an ...
Ginter, James F., Loftis, Patrick
core   +1 more source

Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation [PDF]

, 2000
Background. In this report, we compare the long-term outcome of pediatric liver transplantation (LTx) patients maintained with tacrolimus-based and with cyclosporine (CsA)-based immunosuppressive therapy.
Fung, J, Green, M, Gronsky, C, Jain, A, Kashyap, R, Mazariegos, G, Reyes, J, Starzl, TE   +7 more
core   +1 more source

Enhancing Heart Health: Expanding the Use of SGLT2 Inhibitors in Cardiovascular Disease

Medicine Advances, EarlyView.
SGLT2 inhibitors offer multifaceted cardiovascular benefits, including improved cardiac metabolism, reduced preload and afterload, and decreased myocardial infarction risk. These effects are driven by renoprotection, anti‐inflammatory properties, improved mitochondrial function, osmotic diuresis, and glycemic control. Together, these mechanisms support
Manahil Mubeen, Aasiya Shahbaz Sakarwala, Arif Imdad Bijarani, Muhammad Taha Kamal   +3 more
wiley   +1 more source

Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation

ChemistryOpen, EarlyView.
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco, Maurizio Viale, Graziella Vecchio   +2 more
wiley   +1 more source