Results 61 to 70 of about 49,091 (283)

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, EarlyView.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Safety and Efficacy of Vadadustat Versus Darbepoetin Alfa for Chronic Kidney Disease–Related Anemia in Patients Receiving Dialysis by Baseline Erythropoiesis‐Stimulating Agent Dose

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction Erythropoiesis‐stimulating agents (ESAs) and iron supplementation are standard treatments for chronic kidney disease (CKD)–related anemia. Targeting higher hemoglobin values in CKD increases cardiovascular risk. Whether the increased risk is from higher ESA doses or higher hemoglobin levels is uncertain, but alternative therapies ...
Alan Jardine   +9 more
wiley   +1 more source

Persistent Severe Hyperkalemia in a Patient with Normal Renal Function [PDF]

open access: yes, 2012
Case Report A 75-year-old female with a past medical history significant for hypertension, hyperlipidemia, and colon cancer, status post colectomy with ileostomy, presented to the Methodist Hospital emergency room with muscular low back pain, which ...
Tobin, MD, Michael L.
core   +2 more sources

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova   +2 more
wiley   +1 more source

Pseudohyperkalemia Revisited: An Updated Review of a Foremost Preanalytical Error of Serum or Plasma Potassium Measurement in the Clinical Laboratory

open access: yesNigerian Journal of Medicine
Background: Potassium is one of the most abundant cations in the human body. Increased plasma potassium concentration (hyperkalemia) is one of the most common electrolyte abnormalities in contemporary clinical practice.
Henry Chima Okpara   +2 more
doaj   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Outcomes in Older Inpatients with Hyperkalemia: A Follow-up Observational Study

open access: yesJournal of the Indian Academy of Geriatrics
Objectives: Hyperkalemia is a common electrolyte disturbance encountered in hospitalized older patients secondary to age-related physiological changes in the kidneys, multiple comorbidities, and the burden of multiple medication usage. Metabolic acidosis,
Bharathi Ramesh   +3 more
doaj   +1 more source

When Delirium Unmasks a Silent Myocardial Infarction

open access: yesJournal of the American Geriatrics Society, EarlyView.
Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali   +10 more
wiley   +1 more source

Efficacy and safety of sodium zirconium cyclosilicate in patients with baseline serum potassium level ≥ 5.5 mmol/L: pooled analysis from two phase 3 trials. [PDF]

open access: yes, 2019
BackgroundReliable, timely-onset, oral treatments with an acceptable safety profile for patients with hyperkalemia are needed. We examined the efficacy and safety of sodium zirconium cyclosilicate (SZC; formerly ZS-9) treatment for ≤ 48 h in patients ...
Amin, Alpesh N   +3 more
core  

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