ABSTRACT Objectives Conventional antispasmodics used during endoscopic retrograde cholangiopancreatography (ERCP), such as hyoscine butylbromide and glucagon, are often contraindicated in elderly patients with comorbidities. This trial aimed to assess the efficacy of lidocaine for inhibiting duodenal peristalsis during ERCP.
Masato Suzuki +11 more
wiley +1 more source
Persistent Severe Hyperkalemia in a Patient with Normal Renal Function [PDF]
Case Report A 75-year-old female with a past medical history significant for hypertension, hyperlipidemia, and colon cancer, status post colectomy with ileostomy, presented to the Methodist Hospital emergency room with muscular low back pain, which ...
Tobin, MD, Michael L.
core +2 more sources
MFCN‐DDI: Capsule network based on multimodal feature for multitype drug–drug interaction prediction
Abstract Precise prediction of drug–drug interactions (DDIs) is essential for pharmaceutical research and clinical applications to minimize adverse reactions, optimize therapies, and reduce costs. However, existing methods still face challenges in effectively integrating multidimensional drug features and fully utilizing edge features in molecular ...
Jiayi Lu +5 more
wiley +1 more source
Severe respiratory acidosis contributing to refractory hyperkalemia: a case series of COVID-19 patients with renal failure [PDF]
Introduction: Respiratory acidosis (RA) is not known to cause severe hyperkalemia. However, an exception to this general rule was observed in three patients with severe COVID-19 complicated with renal failure in our center.
Nabadwip Pathak, Sunil Kumar Nanda
doaj +1 more source
Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial [PDF]
Background—The prevalence of pre–diabetes mellitus and its consequences in patients with heart failure and reduced ejection fraction are not known.
Cardoso, José Silva +17 more
core +1 more source
ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert +3 more
wiley +1 more source
Hyperkalemia in the tropics: multiple causes and a not so common presentation—a case report
Background Hyperkalemia is an electrolyte abnormality with potentially life-threatening consequences. But all cases of hyperkalemia need not be symptomatic either.
Abraham M. Ittyachen +4 more
doaj +1 more source
Case Report: Compound Heterozygous SCNN1B Mutations Causing Pseudohypoaldosteronism Type 1B2 in Neonatal Twins. [PDF]
First Chinese neonatal cases of systemic PHA1B from novel compound‐heterozygous SCNN1B variants (c.585+2T>C; c.1544T>C) presented with life‐threatening hyperkalemia and hyponatremia unresponsive to steroids. Early genetic testing enabled targeted sodium supplementation and potassium‐binding therapy, normalizing electrolytes and underscoring SCNN1B ...
Wang Z, Long L, Bi H.
europepmc +2 more sources
When Stability Fails: Rare Very Late Dislodgement of 3830 Lead
ABSTRACT We report a rare case of very late dislodgement of a Medtronic SelectSecure 3830 lumenless lead three years after successful left bundle branch area pacing. An 88‐year‐old patient with permanent atrial fibrillation and bifascicular block underwent VVIR pacemaker implantation in 2022 with excellent initial parameters (threshold 0.8 V at 0.5 ms,
Dilip Kumar +5 more
wiley +1 more source
Background Hyperkalemia has been associated with increased mortality in patients with myocardial infarction, but few data exist regarding hyperkalemia in cardiac intensive care unit (CICU) patients.
Benjamin Brueske +5 more
doaj +1 more source

