Results 51 to 60 of about 50,269 (341)
Arthritis &Rheumatology, Accepted Article.Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein +14 more
wiley +1 more source
DairyMaintaining teat-end integrity in dairy cows is essential to preventing intramammary infections (IMIs) in dairy cows, yet the relationship between hyperkeratosis, teat conformation, and mammary health remais underexplored.
Leonardo Leite Cardozo +8 more
doaj +1 more source
Mutations in desmoglein-1 cause diverse inherited palmoplantar keratoderma phenotypes:implications for genetic screening [PDF]
, 2017 INTRODUCTION: The inherited palmoplantar keratodermas (PPKs) are a heterogeneous group of genodermatoses, characterised by thickening of the epidermis of the palms and soles. No classification system unites satisfactorily clinical presentation, pathology
Almutawa +16 more
core +2 more sources
Nevoid Hyperkeratosis of the Nipple and/or Areola: Treatment with Topical Steroid
Indian Journal of Dermatology, 2013 Nevoid hyperkeratosis of the nipple and/or areola (NHNA) is a rare and benign disease, with poorly understood etiology and no definite therapeutic plan.
A. Ghanadan +3 more
semanticscholar +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
Barrier Immunity, EarlyView.ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
wiley +1 more source
Genetics and Molecular Biology, 2003 We report on a 22-year-old male patient and his father, both presenting with congenital sensorineural deafness, diffuse palmoplantar keratoderma and knuckle pads.
Gisele Viana de Oliveira +3 more
doaj +1 more source
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby
Developmental Dynamics, EarlyView.Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe +3 more
wiley +1 more source
Plantar calluses - pathogenesis, risk factors, prophylaxis, methods of treatment
Journal of Education, Health and Sport, 2018 Calluses are one of the forms of cutaneous hyperkeratosis. The problem of their occurrence applies to people of all ages, with a special tendency among older people. The cause of their formation is local damage to the skin of feet secondary to the impact
Daria Marczak +2 more
doaj +3 more sources
Медицинский совет, 2020 The feet have an increased load, they are often injured, especially with diabetes. Because of the violation of innervation, patients do not notice minor injuries: abrasions, bruises, cracks, cuts.
O. V. Svetlova +3 more
doaj +1 more source
Congenital ichthyosis in a Maltese dog: A case report
Veterinární Medicína, 2021 This case report describes congenital ichthyosis in a Maltese dog, a condition, which has not previously been reported in this breed. The dog presented with several dry, tightly adhering scales showing a multi-focal appearance.
Kim TS +5 more
doaj +1 more source