Results 21 to 30 of about 204,961 (215)
Nutrients, 2022 Astragalus membranaceus (AM) is a food and medicinal homologous plant. The current research is aimed to investigate the beneficial effects and mechanisms of AM in treating acquired hyperlipidemia.
Ling Wang +4 more
semanticscholar +1 more source
Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK and Phosphorylation of Smad2L [PDF]
Cell Journal, 2022 Objective: In addition to the carboxy region, Smad2 transcription factor can be phosphorylated in the linker region aswell. Phosphorylation of Smad2 linker region (Smad2L) promotes the expression of plasminogen activator inhibitor type1 (PAI-1) which ...
hossein babaahmadi rezaei +2 more
doaj +1 more source
EGF Receptor Transactivation by Endothelin-1 Increased CHSY-1 Mediated by NADPH Oxidase and Phosphorylation of ERK1/2 [PDF]
Cell Journal, 2021 Objective: Growth factors [transforming growth factor-β (TGF-β), epidermal growth factor (EGF), endothelin-1 (ET-1)] stimulate proteoglycan synthesis resulting in retention and accumulation of low density lipoprotein (LDL) in vessel intima and leading to
Hossein Babaahmadi-Rezaei +5 more
doaj +1 more source
BMC Research Notes, 2020 Objectives This study focused on the beneficial effects of Capparis spinosa (CS) treatment on the steatohepatitis induced by the administration of a high-fat emulsion in rats.
Rasoul Akbari +4 more
doaj +1 more source
Dietary Fiber: An Opportunity for a Global Control of Hyperlipidemia
Oxidative Medicine and Cellular Longevity, 2021 Dietary fiber has a long history in the intervention study of hyperlipidemia. In this review, current understandings of structures, sources, and natures of various kinds of dietary fibers (DFs) were analyzed first.
Y. Nie, F. Luo
semanticscholar +1 more source
Combination of Silibinin and Curcumin Reduced Leptin Receptor Expression in MCF-7 Human Breast Cancer Cell Line [PDF]
Iranian Journal of Medical Sciences, 2020 Background: Leptin and leptin receptor (Ob-R) are associated with worse prognosis, distant metastasis, and poor survival of breast cancer. We investigated the cytotoxic effect of silibinin and curcumin, individually and combined, on Ob-R expression in ...
Somaye Dalimi-Asl +2 more
doaj +1 more source
BioMed Research International, 2021 Background Yinchen Wuling powder is often used to treat clinical hyperlipidemia, although its mechanism of action remains unclear. In this study, we aimed to investigate the active ingredients found in Yinchen Wuling powder and find its mechanism of ...
Jiahao Ye, Lin Li, Zhixi Hu
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Atorvastatin ester (Ate) is a structural trim of atorvastatin that can regulate hyperlipidemia. The purpose of this study was to evaluate the lipid-lowering effect of Ate.
Nan Hu +5 more
semanticscholar +1 more source
BMC Pharmacology and Toxicology, 2021 Background Vitamin D deficiency is prevalent in patients with non-alcoholic fatty liver disease (NAFLD), but there are debates on the usefulness of vitamin D treatment.
Hamid Yaghooti +4 more
doaj +1 more source
Relationship between Hyperlipidemia, Cardiovascular Disease and Stroke: A Systematic Review
Current Cardiology Reviews, 2020 Background Globally, dyslipidemia has been shown to be an independent predictor of many cardiovascular and cerebrovascular events, which led to recent advocacy towards dyslipidemia prevention and control as a key risk factor and its prognostic ...
Aladeen Alloubani +2 more
semanticscholar +1 more source