Cirrhosis is frequently accompanied by varying degrees of lipid profile abnormalities. This study confirms that these profiles are differentially affected by disease etiology and progressively worsen—with significant reductions in TC, HDL‐C, and LDL‐C—as liver disease severity increases. TIPS improves lipid profiles, particularly by increasing HDL‐C in
Jiamin Xu +6 more
wiley +1 more source
Effects of Intravenous Laser Irradiation of Blood on Metabolic Markers in Patients With Hyperlipidemia: A Retrospective Pilot Study. [PDF]
Huang CY +10 more
europepmc +1 more source
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Pharmacogenomics-based systematic review of coronary artery disease based on personalized medicine procedure. [PDF]
Kazemi Asl S +2 more
europepmc +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Ultrasound measurements of croup fat thickness and liver echogenicity as indicators for lipomobilization in donkeys (Equus Africanus asinus) with fasting-induced hyperlipidemia. [PDF]
Mahmoud AAE, Elsayed HK, Hussein HA.
europepmc +1 more source
Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen +16 more
wiley +1 more source
Comparative Effectiveness of Cholesteryl Ester Transfer Protein (CETP) Inhibitors on Lipid Profiles in Adults With Hyperlipidemia: A Comprehensive Systematic Review and Frequentist Network Meta-Analysis of Randomized Controlled Trials. [PDF]
Khalil I +15 more
europepmc +1 more source
Hepatic fibrosis and metabolic syndrome are more prevalent in PsA patients treated with methotrexate, compared to RA patients. Metabolic syndrome is associated with the risk of hepatic fibrosis in patients diagnosed with PsA and RA even after adjustment forcumulative methotrexate exposure.
Ratchaya Lertnawapan +3 more
wiley +1 more source

