Results 171 to 180 of about 5,561 (244)
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Sitosterol in juvenile type II hyperlipoproteinemia
Atherosclerosis, 1978The effect of beta-sitosterol on plasma lipids and lipoproteins was evaluated in a randomized double-blind cross-over trial in 15 children and adolescents with familial hypercholesterolemia over a period of 6 months. Twelve patients completed the study, with good adherence to drug intake.
G. Schlierf +4 more
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Clinics in Endocrinology and Metabolism, 1973
Type II hyperlipoproteinemia is characterized by an abnormally high plasma β-lipoprotein concentration. Hence, an alternative name for the Type II lipoprotein pattern is hyper-β-lipoproteinemia. Although this pattern commonly occurs in the absence of any other lipoprotein abnormality, it may also occur in association with a raised concentration of ...
Nicolas B. Myant, Joan Slack
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Type II hyperlipoproteinemia is characterized by an abnormally high plasma β-lipoprotein concentration. Hence, an alternative name for the Type II lipoprotein pattern is hyper-β-lipoproteinemia. Although this pattern commonly occurs in the absence of any other lipoprotein abnormality, it may also occur in association with a raised concentration of ...
Nicolas B. Myant, Joan Slack
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Results of colestipol therapy in type II hyperlipoproteinemia
Atherosclerosis, 1976Twenty-five patinets with well defined Type ii hyperlipoproteinemia were treated with a divided 15 g daily dose of colestipol, a bile acid sequestrant, for periods of up to 20 months. The patients were divided into 3 groups: Those with no obvious sequelae, those with arcus corneae, xanthomas, and/or xanthelasmas only, and those with atherosclerotic ...
Ann M. Lees +2 more
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Special Diet for Familial Type II Hyperlipoproteinemia
Archives of Pediatrics & Adolescent Medicine, 1974A suggested diet containing less than 200 mg cholesterol per day, with a polyunsaturate: saturate ratio of 0.9:1 was prepared for young children with familial hypercholesterolemia. A representative meal plan and calculations for a seven-day food intake allow for a practical, economical diet, low in cholesterol and saturated fat, but high in essential ...
Charles J. Glueck +2 more
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Effect of lovastatin on hemorheology in type II hyperlipoproteinemia
Atherosclerosis, 1990To assess the effect of lovastatin on blood rheology, the hemorheological determinants fibrinogen, red cell aggregation, plasma viscosity, hematocrit and platelet aggregation (spontaneous and ADP-induced) were studied in 15 patients with type II hyperlipoproteinemia in the course of treatment with lovastatin.
Erich Minar +2 more
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Controlled trial of acifran in type II hyperlipoproteinemia
Clinical Pharmacology and Therapeutics, 1985The hypolipidemic effects of acifran were evaluated in a randomized, double-blind, placebo-controlled study of 30 patients with type IIa hyperlipoproteinemia. Plasma lipid and lipoprotein values were determined at baseline (mean of three values), again after a 2-week single-blind period of acifran dosing, and at 2-week intervals during a 10-week period
Donald B. Hunninghake +3 more
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Neomycin and plasma lipoproteins in type II hyperlipoproteinemia
Clinical Pharmacology and Therapeutics, 1984Neomycin, a nonabsorbable aminoglycoside antibiotic, has been shown to exert a hypocholesterolemic effect in man. In a 9-mo, double-blind, randomized, crossover, placebo-controlled clinical trial, the effect of neomycin, 2 gm/day, on plasma lipoproteins, as well as its safety, was described in 20 subjects with type II hyperlipoproteinemia. A 15% (50 mg%
Carol A. Romano +14 more
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Neonatal Diagnosis of Familial Type II Hyperlipoproteinemia
Pediatrics, 1976Cord serum prebeta-β-lipoprotein concentrations, was measured in a radial immunodiffusion assay in 303 randomly selected, full-term infants whose parental phenotypes were unknown. Six infants had elevated concentrations, that is above a cut-off limit of 197 mg/100 ml (97.5th percentile).
G E, Andersen, B, Friis-Hansen
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Hypertrophy of liver peroxisomes in type II and type IV hyperlipoproteinemia
Atherosclerosis, 1986A morphometric study on liver biopsies from patients with primary hyperlipoproteinemia (IIa n = 4, IIb n = 7, IV n = 7) and in controls (n = 7) was performed by light and electron microscopy. We found hypertrophy of peroxisomes in all subjects with hyperlipoproteinemia.
Debry G +5 more
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Pseudohomozygous and Pseudoheterozygous Type II Hyperlipoproteinemia
Archives of Pediatrics & Adolescent Medicine, 1976A 4-year-old boy had typical features of homozygous type II hyperlipoproteinemia with planar xanthomas, a plasma cholesterol level greater than 600 mg/dl, and an estimated beta-lipoprotein cholesterol concentration greater than 500 mg/dl. Both he and his sister, who had the biochemical features of the heterozygous state, responded unusually well to a ...
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