Chronic Nonbacterial Osteomyelitis of the Sternocostoclavicular Region in Adults: A Single‐Center Dutch Cohort Study [PDF]
JBMR Plus, 2021 Sternocostoclavicular hyperostosis (SCCH) is a rare autoinflammatory bone disorder caused by chronic nonbacterial osteomyelitis (CNO), which is associated with sclerosis and hyperostosis primarily affecting the sternum, the medial end of the clavicles ...
Ashna IE Ramautar +6 more
doaj +3 more sources
Sternocostoclavicular Hyperostosis: Positive Clinical and Radiological Response on Pamidronate [PDF]
Frontiers in Endocrinology, 2021 BackgroundSternocostoclavicular hyperostosis (SCCH) is a rare disease, constituting a chronic sterile osteomyelitis with elevated bone turnover in the axial skeleton, causing pain and shoulder dysfunction.
Anne T. Leerling +4 more
doaj +6 more sources
Mandibular Osteitis Leading to the Diagnosis of SAPHO Syndrome [PDF]
Case Reports in Radiology, 2018 Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a disorder characterized by pustular skin lesions and osteoarticular lesions.
Tomohiro Kikuchi +4 more
doaj +3 more sources
Diagnostic and therapeutic practices in adult chronic nonbacterial osteomyelitis (CNO) [PDF]
Orphanet Journal of Rare Diseases, 2023 Background Chronic nonbacterial osteomyelitis (CNO) is a rare, and impactful auto-inflammatory bone disease occurring in children and adults. Clinical care for CNO is challenging, as the condition lacks validated classification criteria and evidence ...
A. T. Leerling +5 more
doaj +2 more sources
Upadacitinib in the treatment of SAPHO syndrome: a case report [PDF]
Frontiers in ImmunologySynovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare autoinflammatory disease, is usually defined by musculoskeletal symptoms and cutaneous manifestations.
Yanran Yang, Zhanxue Sun, Yongpeng Ge
doaj +2 more sources
Immunological Characterization of Chronic Nonbacterial Osteomyelitis (CNO) in Adults: A Cross-Sectional Exploratory Study. [PDF]
JBMR Plus, 2023 Generic inflammation parameters like ESR, CRP, platelet and neutrophil count are relatively increased in our adult CNO cohort compared to healthy controls, but stay within absolute reference range. Within patients, vertebral involvement and skin inflammation are associated with more pronounced systemic inflammation as compared to isolated bone ...
Leerling AT +6 more
europepmc +2 more sources
Anterior chest wall in SAPHO syndrome: magnetic resonance imaging findings [PDF]
Arthritis Research & Therapy, 2020 Background The anterior chest wall (ACW) involvement is characteristic of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, yet little research has focused on its magnetic resonance imaging (MRI) findings.
Meiyan Yu +9 more
doaj +2 more sources
Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome with Purely Osteolytic, Not Osteosclerotic, Lesions Mimicking a Malignant Tumor. [PDF]
Case Rep Rheumatol, 2020 Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare inflammatory disorder with multiple phenotypes. The syndrome has identifiable radiologic characteristics that are the most important when making a diagnosis. X‐rays of cases diagnosed with SAPHO syndrome reveal sclerotic lesions or mixed lytic and sclerotic lesions. Pure
Kinoshita H +9 more
europepmc +2 more sources
Treatment-Refractory Sternocostoclavicular Hyperostosis. [PDF]
Clin Med Res, 2017 Sternocostoclavicular hyperostosis (SCCH) is an infrequent chronic inflammatory disorder of the axial skeleton of unknown origin. SCCH goes often unrecognized due to a low level of awareness for the disorder. It typically presents with relapsing and remitting pain in the shoulder, neck, and anterior chest wall area with occasional swelling and ...
Yachoui R, Kreidy M, Parker BJ.
europepmc +4 more sources
Sternocostoclavicular Hyperostosis: An Ill-Recognized Disease. [PDF]
Diagnostics (Basel), 2016 Sternocostoclavicular hyperostosis (SCCH) is an ill-recognized, rarely diagnosed disease. Today, SCCH is widely considered part of the synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. SCCH develops over years with intermittent attacks of pain, swelling, and reddening of the sternocostoclavicular region.
Roed B +4 more
europepmc +3 more sources