Results 1 to 10 of about 209 (109)

Sternocostoclavicular Hyperostosis: Positive Clinical and Radiological Response on Pamidronate [PDF]

Frontiers in Endocrinology, 2021
BackgroundSternocostoclavicular hyperostosis (SCCH) is a rare disease, constituting a chronic sterile osteomyelitis with elevated bone turnover in the axial skeleton, causing pain and shoulder dysfunction.
Natasha M Appelman-Dijkstra, Elizabeth M Winter, Winter Elizabeth M   +2 more
exaly   +8 more sources

Chronic Nonbacterial Osteomyelitis of the Sternocostoclavicular Region in Adults: A Single‐Center Dutch Cohort Study [PDF]

JBMR Plus, 2021
Sternocostoclavicular hyperostosis (SCCH) is a rare autoinflammatory bone disorder caused by chronic nonbacterial osteomyelitis (CNO), which is associated with sclerosis and hyperostosis primarily affecting the sternum, the medial end of the clavicles ...
Ashna IE Ramautar, Natasha M Appelman‐Dijkstra, Shannon Lakerveld, Marielle A Schroijen, Marieke Snel, Elizabeth M Winter, Neveen AT Hamdy   +6 more
doaj   +3 more sources

Mandibular Osteitis Leading to the Diagnosis of SAPHO Syndrome [PDF]

Case Reports in Radiology, 2018
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a disorder characterized by pustular skin lesions and osteoarticular lesions.
Tomohiro Kikuchi, Hiroyuki Fujii, Akifumi Fujita, Tomoko Sugiyama, Hideharu Sugimoto   +4 more
doaj   +3 more sources

Sternocostoclavicular Hyperostosis: An Insufficiently Recognized Clinical Entity [PDF]

Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, 2017
A 79-year-old male chronic hemodialysis patient with no history of central venous catheterization was referred to our hospital with progressive swelling of the left upper limb ipsilateral to a forearm arteriovenous fistula. Radiological assessments revealed marked hyperostosis in the ribs, sternum, and clavicles with well-developed ossification of the ...
Daisuke Nagata, Taro Sugase, Tetsu Akimoto   +2 more
exaly   +5 more sources

Diagnostic and therapeutic practices in adult chronic nonbacterial osteomyelitis (CNO) [PDF]

Orphanet Journal of Rare Diseases, 2023
Background Chronic nonbacterial osteomyelitis (CNO) is a rare, and impactful auto-inflammatory bone disease occurring in children and adults. Clinical care for CNO is challenging, as the condition lacks validated classification criteria and evidence ...
A. T. Leerling, G. Clunie, E. Koutrouba, O. M. Dekkers, N. M. Appelman-Dijkstra, E. M. Winter   +5 more
doaj   +2 more sources

Upadacitinib in the treatment of SAPHO syndrome: a case report [PDF]

Frontiers in Immunology
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare autoinflammatory disease, is usually defined by musculoskeletal symptoms and cutaneous manifestations.
Yanran Yang, Zhanxue Sun, Yongpeng Ge
doaj   +2 more sources

Anterior chest wall in SAPHO syndrome: magnetic resonance imaging findings [PDF]

Arthritis Research & Therapy, 2020
Background The anterior chest wall (ACW) involvement is characteristic of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, yet little research has focused on its magnetic resonance imaging (MRI) findings.
Meiyan Yu, Yihan Cao, Junqiu Li, Yanan Zhang, Yuqian Ye, Lun Wang, Ziwei Huang, Xinyu Lu, Chen Li, Jianwei Huo   +9 more
doaj   +2 more sources

Palmoplantar pustulosis: pathogenesis, differential diagnosis, and treatment. [PDF]

J Dtsch Dermatol Ges
Summary Palmoplantar pustulosis (PPP) is a chronic inflammatory and often painful disease characterized by sterile pustules on the palms and soles, significantly impairing quality of life. Women are more frequently affected than men, and smoking is a major trigger. Under biologic therapies, especially TNF antagonists, a paradoxical PPP may occur.
Mössner R, Fetter T, Sabat R, Mrowietz U, Cramer N, Wilsmann-Theis D.   +5 more
europepmc   +2 more sources

Immunological Characterization of Chronic Nonbacterial Osteomyelitis (CNO) in Adults: A Cross-Sectional Exploratory Study. [PDF]

JBMR Plus, 2023
Generic inflammation parameters like ESR, CRP, platelet and neutrophil count are relatively increased in our adult CNO cohort compared to healthy controls, but stay within absolute reference range. Within patients, vertebral involvement and skin inflammation are associated with more pronounced systemic inflammation as compared to isolated bone ...
Leerling AT, Andeweg EH, Faber J, Streefland TCM, Dekkers OM, Appelman-Dijkstra NM, Winter EM.   +6 more
europepmc   +2 more sources

Enteropathic SAPHO Syndrome in Ulcerative Colitis Responsive to Bisphosphonates. [PDF]

Case Rep Rheumatol
SAPHO syndrome, a rare inflammatory disorder of bone, joints, and skin, is named based on the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis. The hallmark of SAPHO syndrome includes osteoarticular and dermatologic manifestations, however, rarer associations with inflammatory bowel disease (particularly Crohn’s disease) have been ...
Phillipps J, Mumtaz S, Valecha J, Stanborough RO, Berianu F, Abate E, Majithia V.   +6 more
europepmc   +2 more sources