Results 1 to 10 of about 4,903,971 (217)

Hyperparathyroidism (primary) NICE guideline: diagnosis, assessment, and initial management. [PDF]

Br J Gen Pract, 2020
Parathyroid hormone (PTH) is secreted from four parathyroid glands situated behind the thyroid gland. PTH regulates calcium and phosphate levels by its promotion of phosphate excretion and calcium reabsorption in the kidneys; stimulation of osteoclastic ...
Jawaid I, Rajesh S.
europepmc   +2 more sources

Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus [PDF]

Osteoporosis International, 2016
The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism.
Bandeira, F., Bhadada, S.K., Bilezikian, J.P., Bollerslev, J., Bouillon, R., Brandi, M.L., Clarke, B.L., Cusano, N.E., D Amour, P., Davison, K.S., Duh, Q., Eastell, R., Goltzman, D., Hanley, D.A., Kaiser, S., Khan, A.A., Kung, A.W., Lewiecki, E.M., Liu, J., Marcocci, C., Mosekilde, L., Paul, T., Potts, J.T., Rao, S.D., Rejnmark, L., Rizzoli, R., Shrayyef, M.Z., Silverberg, S.J., Thakker, R., Udelsman, R., van Uum, S., Young, J.E.M.   +31 more
core   +6 more sources

Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?

Clinical Medicine Insights: Endocrinology and Diabetes, 2018
Asymptomatic primary hyperparathyroidism is a very common endocrine condition, yet management of this disease process remains controversial. Primary hyperparathyroidism can lead to a myriad of symptoms which not only decreases the quality of life of ...
Alexandria D McDow, Rebecca S Sippel
doaj   +2 more sources

A Lost Opportunity: Early Nephrolithiasis as a Missed Indicator of Primary Hyperparathyroidism Over Eight Years [PDF]

Clinical Case Reports
Primary hyperparathyroidism may present with a diagnostic challenge due to its nonspecific initial symptoms, often delaying diagnosis. Nephrolithiasis, a common presentation, is often treated in isolation without consideration of an underlying ...
Prince Yaw Boahene, Solomon Gyabaah, Seth Kyei‐Fram, Paulinus Domeh, Afia Serwaa Bonsu, Bernard C. Nkum   +5 more
doaj   +2 more sources

Brown tumor of the mandible - a possible clinical manifestation of primary hyperparathyreoidism [PDF]

Vojnosanitetski Pregled, 2023
Introduction. One of the possible manifestations of primary hyperparathyroidism (PHPT) is the appearance of a benign bone tumor. We hereby present a case of a young woman whose first clinical manifestation of PHPT was a brown tumor of the mandible.
Milankov Andrijana, Mitrović Milena, Ičin Tijana, Bajkin Branislav, Milankov Vukadin   +4 more
doaj   +1 more source

Biochemistry in Symptomatic and Asymptomatic Primary Hyperparathyroidism: A Cross-Sectional Study

Revista Mexicana de Endocrinología, Metabolismo y Nutrición, 2021
Background: PHPT can be symptomatic or asymptomatic, according to the presence of classic symptoms (skeletal or renal involvement), without conclusive evidence of its relation to biochemical parameters.
Tania K. Cázares Robles, Rocío Fernández-Posada de la Mora, Manuel A Gómez-Martínez, Adriana Rodríguez-Gómez, Ernesto A. Rojas-Jiménez   +4 more
doaj   +1 more source

Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop

Journal of Bone and Mineral Research, 2022
The last international guidelines on the evaluation and management of primary hyperparathyroidism (PHPT) were published in 2014. Research since that time has led to new insights into epidemiology, pathophysiology, diagnosis, measurements, genetics ...
J. Bilezikian, Aliya A. Khan, S. Silverberg, G. E. Fuleihan, C. Marcocci, S. Minisola, N. Perrier, A. Sitges-Serra, R. Thakker, G. Guyatt, M. Mannstadt, J. T. Potts, B. Clarke, M. Brandi   +13 more
semanticscholar   +1 more source

Primary hyperparathyroidism

Nature Reviews Endocrinology, 2018
Background Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women. The clinical presentation of PHPT has evolved over the past 40 years to include three distinct clinical phenotypes ...
M. Walker, S. Silverberg
semanticscholar   +5 more sources

Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, 2022
In this narrative review, we present data gathered over four decades (1980–2020) on the epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT).
S. Minisola, Andrew Arnold, Z. Belaya, M. Brandi, B. Clarke, F. Hannan, L. Hofbauer, K. Insogna, A. Lacroix, U. Liberman, A. Palermo, J. Pepe, R. Rizzoli, R. Wermers, R. Thakker   +14 more
semanticscholar   +1 more source

Classical and Nonclassical Manifestations of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, 2022
This narrative review summarizes data on classical and nonclassical manifestations of primary hyperparathyroidism (PHPT). It is based on a rigorous literature search, inclusive of a Medline search for systematic reviews from 1940 to December 2020 ...
G. E. El-Hajj Fuleihan, M. Chakhtoura, C. Cipriani, R. Eastell, T. Karonova, Jian-min Liu, S. Minisola, A. Mithal, C. Moreira, M. Peacock, M. Schini, Barbara C. Silva, M. Walker, Ola El Zein, C. Marcocci   +14 more
semanticscholar   +1 more source