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Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium.
Grzegorz J. Kowalski +4 more
doaj +8 more sources
Hyperparathyroidism (primary) NICE guideline: diagnosis, assessment, and initial management. [PDF]
Parathyroid hormone (PTH) is secreted from four parathyroid glands situated behind the thyroid gland. PTH regulates calcium and phosphate levels by its promotion of phosphate excretion and calcium reabsorption in the kidneys; stimulation of osteoclastic ...
Jawaid I, Rajesh S.
europepmc +2 more sources
Primary hyperparathyroidism (PHPT) is a common endocrinological process, characterized by chronic elevation of serum concentrations of calcium and parathyroid hormone (PTH). Many years ago, the most frequent forms of clinical presentation were symptomatic renal or skeletal disease with moderate or severe hypercalcemia; however, currently, most patients
Manuel, Muñoz-Torres +1 more
semanticscholar +15 more sources
Primary Hyperparathyroidism [PDF]
Abstract Primary hyperparathyroidism is a common endocrine disease characterized by excessive secretion of parathyroid hormone from one or more of the four parathyroid glands. In most patients, a single, benign adenoma is responsible for the disease, but in a small percentage of subjects, four-gland hyperplasia is evident.
J. Bilezikian
semanticscholar +7 more sources
Primary hyperparathyroidism [PDF]
Key Clinical Message We report a case of hyperparathyroidism with hypercalcemia caused by a giant parathyroid adenoma. We use a technetium sestamibi scan to locate parathyroid mass.
Ao Wang, Lei Yuan
doaj +4 more sources
Normocalcemic primary hyperparathyroidism
Normocalcemic primary hyperparathyroidism (PHPT) is a newer phenotype of PHPT defined by elevated PTH concentrations in the setting of normal serum calcium levels.
Natalie E. Cusano, Filomena Cetani
doaj +2 more sources
Primary hyperparathyroidism [PDF]
In this Review, we describe the pathogenesis, diagnosis and management of primary hyperparathyroidism (PHPT), with a focus on recent advances in the field. PHPT is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone.
Marcella D, Walker, Shonni J, Silverberg
openaire +3 more sources
Primary hyperparathyroidism [PDF]
Primary hyperparathyroidism is a common endocrine disorder caused by overactivation of parathyroid glands resulting in excessive release of parathyroid hormone. The resultant hypercalcemia leads to a myriad of symptoms. Primary hyperparathyroidism may increase a patient's morbidity and even mortality if left untreated.
Madkhali, Tarıq +3 more
+14 more sources
Brown tumor of the mandible - a possible clinical manifestation of primary hyperparathyreoidism [PDF]
Introduction. One of the possible manifestations of primary hyperparathyroidism (PHPT) is the appearance of a benign bone tumor. We hereby present a case of a young woman whose first clinical manifestation of PHPT was a brown tumor of the mandible.
Milankov Andrijana +4 more
doaj +1 more source
Biochemistry in Symptomatic and Asymptomatic Primary Hyperparathyroidism: A Cross-Sectional Study
Background: PHPT can be symptomatic or asymptomatic, according to the presence of classic symptoms (skeletal or renal involvement), without conclusive evidence of its relation to biochemical parameters.
Tania K. Cázares Robles +4 more
doaj +1 more source

