Results 101 to 110 of about 4,903,971 (217)

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Primary Hyperparathyroidism in Pregnancy: Successful Parathyroidectomy during First Trimester

Case Reports in Endocrinology, 2018
Primary hyperparathyroidism in pregnancy can result in significant maternal and fetal complications. When indicated, prompt parathyroidectomy in the early second trimester is considered the treatment of choice.
Niranjan Tachamo, Bidhya Timilsina, Rashmi Dhital, Theresa Lynn, Vasudev Magaji, Ilan Gabriely   +5 more
doaj   +1 more source

Effect of eplerenone on parathyroid hormone levels in patients with primary hyperparathyroidism: a randomized, double-blind, placebo-controlled trial [PDF]

, 2012
Background Increasing evidence suggests the bidirectional interplay between parathyroid hormone and aldosterone as an important mechanism behind the increased risk of cardiovascular damage and bone disease observed in primary hyperparathyroidism.
A Struthers, A Tomaschitz, A Tomaschitz, A Tomaschitz, A Tomaschitz, A Tomaschitz, AA Zia, Albrecht Schmidt, Andreas Meinitzer, Andreas Tomaschitz, AS Mihailidou, Astrid Fahrleitner-Pammer, B Pitt, Burkert Pieske, C Letizia, C Maniero, CA Feldstein, Caterina Colantonio, CG Ogard, CS Fox, DA Sica, E Hagstrom, E Rodriguez-Ayala, Eberhard Ritz, Elisabeth Kraigher-Krainer, F Edelmann, FP Cappuccio, G Mazzocchi, HN Hulter, IL Nilsson, J Lemann Jr, J Rosenberg, JJ McMurray, JM Moseley, JN Cooper, JP Bilezikian, Jörg H Horina, K Amrein, K Olgaard, Karin Amrein, Katharina Kienreich, L Brunaud, L Kovacs, L Morfis, LD Carbone, MH Weinberger, MR Rubin, Nicolas Verheyen, PH Law, R Eastell, R Pacifici, RA Wermers, S Pilz, S Pilz, S Pilz, S Pilz, S van Diepen, SJ Silverberg, Stefan Pilz, T Koal, VS Chhokar, YM Yoo   +61 more
core   +3 more sources

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Primary Hyperparathyroidism: lessons from two cases

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2019
Primary hyperparathyroidism (PHPT) is the most common cause of  hypercalcemia and is characterized by hypercalcemia and levels of parathyroid hormone (PTH) that are inappropriately high for the hypercalcemic state.
Giuseppe Turiano, Astrid Herberg
doaj   +1 more source

Hyperparathyroidism and hyperfunctioning supernumary glands : considerations for challenging management [abstract] [PDF]

, 2010
Hyperparathyroidism can be treated surgically with high success rates. While the majority of patients have four glands, the presence of a supernumerary gland may be encountered as a normal anatomic variant in up to 13% of the population.
Page, Matthew, Showmaker, Jason
core  

Urinary Calcium Measurement in Patients With Hypercalcaemia; Endocrine Physicians and Surgeons Survey Results From UK

Clinical Endocrinology, Volume 103, Issue 5, Page 757-760, November 2025.
ABSTRACT Background In patients with hypercalcaemia, assessment of urinary calcium excretion helps differentiate primary hyperparathyroidism (PHPT) from familial hypocalciuric hypercalcaemia (FHH). For this, 24 h calcium to creatinine clearance ratio (CCCR) is recommended, but others tests like random CCCR, 24 h urine calcium excretion (UCE), and ...
Muhammad Fahad Arshad, Saba P. Balasubramanian   +1 more
wiley   +1 more source

Prevalence of Metabolic Syndrome in Primary Hyperparathyroidism

Haseki Tıp Bülteni, 2017
Aim: In this study, we aimed to evaluate the prevalence of metabolic syndrome (MetS), metabolic abnormalities and independent predictors of MetS in primary hyperparathyroidism and to contribute to long-term follow-up and management of these patients ...
Gökçen Tuğba Çevik, Sibel Güldiken, Neslihan Soysal Atile, Hüseyin Çelik, Mehmet Çelik, Semra Aytürk, Necdet Süt, Ayşe Armağan Tuğrul   +7 more
doaj   +1 more source

Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis [PDF]

, 2019
Background: Etelcalcetide is an intravenous calcimimetic approved for treatment of secondary hyperparathyroidism (sHPT) in patients receiving hemodialysis. Besides lowering parathyroid hormone (PTH), etelcalcetide also significantly reduces fibroblast
Block, Geoffrey A., Chertow, Glenn M., Cooper, Kerry, Fouqueray, Bruno, Moe, Sharon M., Oberbauer, Rainer, Sun, Yan, Tomlin, Holly, Vervloet, Marc, Wolf, Myles   +9 more
core   +1 more source

Cardiovascular Morbidity in Patients Undergoing Successful Surgery for Primary Hyperparathyroidism

Clinical Endocrinology, Volume 103, Issue 5, Page 669-681, November 2025.
ABSTRACT Objective Although previous studies have shown reduced cardiovascular events following parathyroidectomy (PTX), it is unclear whether this extends to contemporary patients diagnosed and treated with milder disease than previously. The aim of this nation‐wide study was to determine the effect on cardiovascular events after PTX, and to ...
Martin Nilsson, J. Gustav Smith, Mark Thier, Erik Nordenström, Anders Bergenfelz, Martin Almquist   +5 more
wiley   +1 more source