Results 61 to 70 of about 4,810,159 (239)

Primary decomposition of modules: a computational differential approach [PDF]

arXiv, 2021
We study primary submodules and primary decompositions from a differential and computational point of view. Our main theoretical contribution is a general structure theory and a representation theorem for primary submodules of an arbitrary finitely generated module over a polynomial ring.
arxiv  

Phenotypical Characterization of Gastroenterological and Metabolic Manifestations in Patients With Williams–Beuren Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gastrointestinal (GI) symptoms are common in patients with Williams–Beuren syndrome (WBS), but their prevalence and possible causes are not yet fully known. This study assessed GI symptoms' prevalence and their possible origin by performing a predefined set of tests in adult WBS patients.
Maria Francesca Bedeschi, Annarita Baldassarri, Roberta Villa, Federico Tanzi, Simona Salera, Vincenza Lombardo, Alessandro Draghi, Nicole Piazza O'Sed, Giovanni Casazza, Maurizio Vecchi, Mirella Fraquelli   +10 more
wiley   +1 more source

Changes in clinical patterns of Chinese patients with primary hyperparathyroidism in the past 12 years: a single-center experience

Endocrine Connections, 2021
The clinical presentation of primary hyperparathyroidism (PHPT) differs between patients from developed and developing countries. In China, the clinical pattern has changed over the past few decades.
Yuan Liu, Siyi Guo, Jinsong Wu, Rongai Wang, Jinbo Liu, Yan Liu, Bin Lv, Nan Liu, Ling Jiang, Xiaoli Zhang   +9 more
doaj   +1 more source

S-1-absorbing primary submodules [PDF]

arXiv, 2022
In this work, we introduce the notion of $S$-1-absorbing primary submodule as an extension of 1-absorbing primary submodule. Let $S$ be a multiplicatively closed subset of a ring $R$ and $M$ be an $R$-module. A submodule $N$ of $M$ with $(N:_{R}M)\cap S=\emptyset$ is said to be $S$-1-absorbing primary if whenever $abm\in N$ for some non-unit $a,b\in R$
arxiv  

Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson, Frank Mentch, Jonathan Billings, Kayleigh Ostberg, Michael E. March, Jennifer M. Kalish, Dong Li, India Cannon, Lisa M. Guay‐Woodford, Erum Hartung, Alanna Strong   +10 more
wiley   +1 more source

Diabetes mellitus, chronic pancreatitis and primary hyperparathyroidism: is there a connection?

Сахарный диабет, 2019
Hyperparathyroidism is a relatively frequent condition characterized by hypersecretion of parathyroid hormone. There are several forms of primary hyperparathyroidism. Each form affects its target region.
Anna M. Gorbacheva, Nataliya V. Zaytseva
doaj   +1 more source

Intraoperative Parathyroid Hormone Monitoring in the Surgical Management of Sporadic Primary Hyperparathyroidism [PDF]

Endocrinology and Metabolism, 2019
Intraoperative parathyroid hormone monitoring (IPM) has been shown to be a useful adjunct during parathyroidectomy to ensure operative success at many specialized medical centers worldwide. Using the Miami or “>50% intraoperative PTH drop” criterion, IPM
Zahra F. Khan, John I. Lew
doaj   +1 more source

Protective Effect of Denosumab on Bone in Older Women with Primary Hyperparathyroidism

Journal of The American Geriatrics Society, 2018
To determine the effect of denosumab, which is used in primary osteoporosis (PO), in primary hyperparathyroidism (PHPT)‐related osteoporosis.
C. Eller-Vainicher, S. Palmieri, E. Cairoli, G. Goggi, A. Scillitani, M. Arosio, A. Falchetti, I. Chiodini   +7 more
semanticscholar   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe Bornscheuer   +4 more
wiley   +1 more source