Results 101 to 110 of about 25,820 (298)

The Case | Ectopic calcifications in a child [PDF]

, 2015
The case A nine year old boy, born of third degree consanguinity, presented with a hard left scapular swelling for 6 months. There was no history of fever, trauma or weight loss. There was no pain, redness or discharge. This mass was excised but recurred
Econs, Michael J., Hase, Niwrutti K., Imel, Erik A., Jamale, Tukaram E., Keskar, Vaibhav S., Kulkarni, Manjunath, Mane, Swati   +6 more
core   +2 more sources

Kolonoskopiyi Takiben Gelişen Akut Fosfat Nefropati Olgusu

Sakarya Tıp Dergisi, 2017
Fosfat nefropatisi fosfat kristallerinin nefronları hasara uğratması sonucu gelişen akut böbrek yetmezliğine verilen addır. Kolonun direk incelenmesini sağlayan kolonoskopi işlemiçeşitli endikasyonlar nedeniyle sıkça uygulanmaktadır.
Mehmet Yıldırım, Seyyid Bilal Açıkgöz, Fatma İnci Can, Ahmet Nalbant, Hakan Cinemre, Ali Tamer   +5 more
doaj   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Genetic evidence of serum phosphate-independent functions of FGF-23 on bone [PDF]

, 2011
Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal mineralization.
Bergwitz, Clemens, Erben, Reinhold G., Kim, Somi, Lanske, Beate Klara Maria, Razzaque, Mohammed Shawkat, Schüler, Christiane, Sitara, Despina, Taguchi, Takashi   +7 more
core   +1 more source

Microdose Cocktail Study Reveals the Activity and Key Influencing Factors of OATP1B, P‐Gp, BCRP, and CYP3A in End‐Stage Renal Disease Patients

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1303-1312, May 2025.
OATP1B, P‐gp, BCRP, and CYP3A are the most contributing drug‐metabolizing enzymes or transporters (DMETs) for commonly prescribed medication. Their activities may change in end‐stage renal disease (ESRD) patients with large inter‐individual variabilities (IIVs), leading to altered substrate drug exposure and ultimately elevated safety risk.
Weijie Kong, Yuejuan Pan, Yujie Wu, Yiyi Hu, Zhenbin Jiang, Xinkui Tian, Shuhong Bi, Song Wang, Feifei Feng, Yuyan Jin, Jiayu Li, Haiyan Li, Yue Wang, Hao Liang, Wen Tang, Dongyang Liu   +15 more
wiley   +1 more source

A Causal Association Study Between Chronic Kidney Disease and Oral Health: A Mendelian Randomization Study

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Previous studies have shown that chronic kidney disease (CKD) can lead to changes in oral health, but the conclusions remain controversial. Thus, we conducted a Mendelian randomization (MR) study from the perspective of genetic analysis to assess the causal association between CKD and oral health conditions, including ...
Guilian Zhang, Duojiao Xu, Guoxia Yu
wiley   +1 more source

Phosphate stimulates myotube atrophy through autophagy activation: evidence of hyperphosphatemia contributing to skeletal muscle wasting in chronic kidney disease

BMC Nephrology, 2018
BackgroundAccelerated muscle atrophy is associated with a three-fold increase in mortality in chronic kidney disease (CKD) patients. It is suggested that hyperphosphatemia might contribute to muscle wasting, but the underlying mechanisms remain unclear ...
Yue-yue Zhang, Man Yang, J. Bao, L. Gu, Hong-Lei Yu, W. Yuan   +5 more
semanticscholar   +1 more source

Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients. [PDF]

, 2012
INTRODUCTION Numerous studies have attempted to identify risk factors for mortality and morbidity in maintenance hemodialysis patients. In this study we sought to examine the association of the levels of serum C-reactive protein (CRP) with value of Ca×
Nasri, H.
core   +1 more source

Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium [PDF]

, 2014
Mutations in the GALNT3 gene result in familial tumoral calcinosis, characterized by persistent hyperphosphatemia and ectopic calcific masses in soft tissues.
Gray, Amie K., Ichikawa, Shoji, Moe, Sharon M., Reilly, Austin M.   +3 more
core   +1 more source

Successful Pregnancy Management of a Woman With Severe Methylmalonic Acidemia

JIMD Reports, Volume 66, Issue 3, May 2025.
ABSTRACT Isolated methylmalonic acidemia (MMA) is a rare, genetically heterogeneous group of metabolic disorders resulting from a deficiency of the enzyme methylmalonyl‐CoA mutase (MMUT), defects in the metabolism of its cofactor, adenosylcobalamin, or deficiency of the enzyme methylmalonyl‐CoA epimerase. With improved awareness, earlier diagnosis, and
M. Woidy, K. Tsiakas, M. Mahmud, G. Eich, S. Loos, J. Lisfeld, S. Schultz, A. C. Tallarek, K. Hecher, T. B. Huber, A. C. Muntau, G. Gramer   +11 more
wiley   +1 more source