Results 151 to 160 of about 663,937 (405)

PLF‐1 (Proliferin‐1) Modulates Smooth Muscle Cell Proliferation and Development of Experimental Intimal Hyperplasia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Although apoptosis and cell proliferation have been extensively investigated in atherosclerosis and restenosis postinjury, the communication between these 2 cellular events has not been evaluated.
Lina Hu, Zhe Huang, Hideki Ishii, Hongxian Wu, Susumu Suzuki, Aiko Inoue, Weon Kim, Haiying Jiang, Xiang Li, Enbo Zhu, Limei Piao, Guangxian Zhao, Yanna Lei, Kenji Okumura, Guo‐Ping Shi, Toyoaki Murohara, Masafumi Kuzuya, Xian Wu Cheng   +17 more
doaj   +1 more source

Tissue fibrosis: a principal proof for the central role of Misrepair in aging [PDF]

arXiv, 2015
Tissue fibrosis is the phenomenon that a tissue has progressive deposition of collagen fibers with age. Tissue fibrosis is associated with aging of most of our organs, and it is the main pathology in arteriosclerosis, chronic bronchitis/emphysema, and benign prostatic hyperplasia.
arxiv  

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Sebaceous hyperplasia: systemic treatment with isotretinoin*

Anais Brasileiros de Dermatologia, 2015
The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day.
Sandra Tagliolatto, Octavio de Oliveira Santos, M. Alchorne, M. Enokihara   +3 more
semanticscholar   +1 more source

Acute urinary retention due to benign prostatic hyperplasia associated with cystitis glandularis in a 22-year-old patient

The Pan African Medical Journal, 2018
A 22-year-old man has consulted in emergency for acute urinary retention and left renal colic. Bladder catheterization was performed. Symptomatic treatment was provided with no improvement.
Skander Zouari, Khaireddine Bouassida, Khaled Ben Ahmed, Ahlem Bdioui Thabet, Mohamed Amine Krichene, Chawki Jebali   +5 more
doaj   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

Congenital Adrenal Hyperplasia: A Case Report with Premature Teeth Exfoliation and Bone Resorption [PDF]

, 2015
Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol. The aim of this case report was to present a child with CAH, premature exfoliation of primary teeth and accelerated ...
Angelopoulou, Matina V., Emmanouil, Dimitris E., Kontogiorgos, Elias D.   +2 more
core   +1 more source

Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in normal and pathological human oral mucosa

Folia Histochemica et Cytobiologica, 2010
Cyclooxigenase (COX) is the rate-limiting enzyme for the conversion of arachidonic acid (AA) to prostaglandins(PGs). Two isoforms of COX have been identified: COX-1 is constitutively expressed in many cells and is involved in cellhomeostasis ...
Annamaria Mauro, Luana Lipari, Angelo Leone, Silvia Tortorici, Francesco Burruano, Salvatore Provenzano, Aldo Gerbino, Maria Buscemi   +7 more
doaj  

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

FURTHER STUDIES ON THE TREATMENT OF CONGENITAL ADRENAL HYPERPLASIA WITH CORTISONE: V. EFFECTS OF CORTISONE THERAPY ON TESTICULAR DEVELOPMENT*† [PDF]

, 1954
Lawson Wilkins, José Cara
openalex   +1 more source