Results 221 to 230 of about 61,022 (308)

Functional development of photoreceptors in human retinal organoids. [PDF]

Stem Cell Res Ther
Zhang Y, Du M, Wang YH, Li M, Jin K, Pan D, Zhang X, Jin ZB.   +7 more
europepmc   +1 more source

Repeatability of Metabolic Imaging With Hyperpolarized Pyruvate: Back‐to‐Back Neuroimaging and Blood Analysis

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 548-556, August 2026.
ABSTRACT Purpose 13C MRI with hyperpolarized [1‐13C]pyruvate enables noninvasive imaging of metabolic pathways. Considering the high dose of pyruvate used in hyperpolarized 13C‐pyruvate studies, circulating 13C‐pyruvate and the resulting 13C‐lactate in plasma may influence subsequent pyruvate metabolism, yet the guidance on consecutive injections does ...
Jun Chen, Sung‐Han Lin, Jessica Sudderth, Kelley A. Derner, Crystal E. Harrison, Maheen Zaidi, Jeannie D. Baxter, Jeff Liticker, Zohreh Erfani, Craig R. Malloy, Marco C. Pinho, Ralph J. DeBerardinis, Jae Mo Park   +12 more
wiley   +1 more source

Endothelial triple-pathway vasorelaxation as an adjunctive strategy in resistant hypertension. [PDF]

J Hypertens
Madeddu P, Cattaneo M, Giuffre M, Laffin LJ.   +3 more
europepmc   +1 more source

A System for Retrofitting Conventional MRI Systems for Simultaneous Multinuclear MRI/MRS

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
We present a low‐cost system for retrofitting conventional narrow‐band MRI spectrometers with simultaneous multinuclear capability using heterodyne frequency translation. The system supports up to four nuclei and 16 receive channels, with reconfigurable transmit modes and inherent phase stability through a shared local oscillator architecture ...
Jue Hou, Courtney Bauer, Edith Touchet‐Valle, Mary P. McDougall, Steven M. Wright   +4 more
wiley   +1 more source

Cerebral capillary computation. [PDF]

Am J Physiol Cell Physiol
Longden TA.
europepmc   +1 more source

Hyperpolarized MRI Detects Increased [1‐13C]Pyruvate Metabolism in Early Liver Regeneration

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Hyperpolarized [1‐13C]pyruvate MRI detected increased pyruvate‐to‐lactate and pyruvate‐to‐alanine exchange during early liver regeneration following 70% partial hepatectomy in rats. These findings support the use of hyperpolarized MRI for noninvasive assessment of regenerative metabolism.
Uffe Kjærgaard, Andrea Lund, Lotte Bonde Bertelsen, Esben Søvsø Szocska Hansen, Katrine Holm Andersen, Steffen Ringgaard, Jens Randel Nyengaard, Frank Viborg Mortensen, Christoffer Laustsen   +8 more
wiley   +1 more source

Open-Source Multinuclear Low-Field Preclinical MRI Scanner. [PDF]

NMR Biomed
Rodriguez GG, Korchak S, von Petersdorff-Campen C, Sucre O, Felger J, Mei R, Glöggler S.   +6 more
europepmc   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Flecainide binding dynamics in voltage‐gated sodium channels: A comparative isoform analysis of the state‐dependent block

British Journal of Pharmacology, Volume 183, Issue 15, Page 4145-4162, August 2026.
Background and Purpose Local anaesthetics and class I anti‐arrhythmic drugs block voltage‐gated Na+ channels, but the molecular basis for the isoform differences in drug sensitivity remains unclear. Understanding these mechanisms is essential for optimizing therapeutic efficacy and safety.
Tatsuo Munakata, Etsuko Kumada, Nao Katayama, Hiroki Nakagawa, Akihiko Sunami   +4 more
wiley   +1 more source

Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms. [PDF]

J Neuroendocrinol
Lavoie O, Turmel A, Khouma A, Minbashi Moeini M, Liu C, Michael NJ, Caron A.   +6 more
europepmc   +1 more source