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Galactorrhea and Hyperprolactinemia
Obstetrical & Gynecological Survey, 1983Galactorrhea refers to the secretion of a milky fluid from the breast occurring either spontaneously or with manual expression in the absence of pregnancy or the postpartum state. The development of a sensitive and specific radioimmunoassay for human prolactin during the last decade along with improved neuroradiologic techniques have greatly expanded ...
Roland Sakiyama, Martin Quan
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Treatments in Endocrinology, 2003
Hyperprolactinemia is commonly found in both female and male patients with abnormal sexual and/or reproductive function or with galactorrhea. If serum prolactin levels are above 200 microg/L, a prolactin-secreting pituitary adenoma (prolactinoma) is the underlying cause, but if levels are lower, differential diagnoses include the intake of various ...
Howard A. Zacur, Jeremy A. King
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Hyperprolactinemia is commonly found in both female and male patients with abnormal sexual and/or reproductive function or with galactorrhea. If serum prolactin levels are above 200 microg/L, a prolactin-secreting pituitary adenoma (prolactinoma) is the underlying cause, but if levels are lower, differential diagnoses include the intake of various ...
Howard A. Zacur, Jeremy A. King
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Headache, Hyperprolactinemia, and Prolactinomas
Obstetrical & Gynecological Survey, 1987The present study was undertaken to investigate whether headache in women with nonpuerperal hyperprolactinemia was related to elevated serum prolactin (PRL) levels or the presence of a PRL-secreting pituitary adenoma. The subjects were 469 women seen initially during the period of 1973 to 1979 at four clinical centers with the complaints of secondary ...
Peter M. Strebel +2 more
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Hyperprolactinemia in postmenopausal women
Fertility and Sterility, 1997To study the clinical cause and course of hyperprolactinemia in postmenopausal women.Retrospective case-note study.Tertiary care hospital.Six postmenopausal women with hyperprolactinemia.Clinical history and physical examination, serum levels of PRL, LH, FSH, computed tomography (CT) of the pituitary gland before and after treatment with bromocriptine ...
Yasmin Maor, Meir Berezin
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Depression and hostility in hyperprolactinemia
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 19821. Patients with hyperprolactinemia offer a unique opportunity to investigate the effects of prolactin on psychological states. Women with hyperprolactinemic amenorrhea rated themselves significantly more hostile, more depressed and more anxious than women with amenorrhea only and normal women. 2.
Robert Kellner +9 more
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Somatotropin secretion in hyperprolactinemia
Neuroscience and Behavioral Physiology, 19831. HPL patients characteristically show depressed basal levels of STH. 2. Patients with HPL and radiologically confirmed pituitary adenoma show an altered response of the somatotropic structures to glucose challenge and marked circadian variations in the STH circadian pattern. 3.
Sabakhtarashvili Ma +4 more
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Hyperprolactinemia and Delusion of Pregnancy
Psychopathology, 2007We describe the case of a 44-year-old woman admitted with mania with psychotic symptoms who presented with delusion of twin pregnancy a month after admission, which temporally correlated with hyperprolactinemia secondary to antipsychotic medication. Modification of antipsychotic medication was associated with fall in serum prolactin and disappearance ...
Ahuja N, Vasudev K, Lloyd A
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Metabolic Syndrome in Hyperprolactinemia
2018The metabolic syndrome (MetS) is a conglomerate of clinical findings that convey into increased morbidity and mortality from type 2 diabetes mellitus (T2D) and cardiovascular disease. Hyperprolactinemia (hyperPRL) is associated with components of MetS, especially during pregnancy.
Andersen, Marianne, Glintborg, Dorte
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Endocrinology and Metabolism Clinics of North America, 1992
Unlike other pituitary hormones, PRL is under tonic inhibition by the hypothalamus by way of the PRL inhibitory factor, dopamine. GAP and GABA may also be inhibitory. PRL-releasing factors include TRH and VIP and possibly others. Circulating PRL is predominantly monomeric, although some patients with hyperprolactinemia appear to have increased ...
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Unlike other pituitary hormones, PRL is under tonic inhibition by the hypothalamus by way of the PRL inhibitory factor, dopamine. GAP and GABA may also be inhibitory. PRL-releasing factors include TRH and VIP and possibly others. Circulating PRL is predominantly monomeric, although some patients with hyperprolactinemia appear to have increased ...
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Hyperprolactinemia and prolactinoma
2014Prolactinomas are the most frequent pituitary adenomas. In patients with prolactinomas the primary cause of hyperprolactinemia is excessive and autonomic production of prolactin by lactotroph cells. In other conditions, except in case of macroprolactinemia, hyperprolactinemia is secondary to circumstances that stimulate secretion of prolactin by ...
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