Results 61 to 70 of about 21,724 (252)
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, EarlyView.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
International Journal of Cancer, Volume 156, Issue 11, Page 2178-2187, 1 June 2025.What's new? Bone metastases are common in a variety of cancer types, causing increased pain and worse outcomes. Suppression of bone turnover, such as with the monoclonal antibody denosumab, results in fewer skeletal complications and improved prognosis. Here, the authors demonstrate the safety and efficacy of a similar antibody, JMT103. Like denosumab,
Ran Ran +15 more
wiley +1 more source
Macroprolactinemia: a mini-review and update on clinical practice
F&S Reports, 2023 Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D. +4 more
doaj
International journal of psychiatry in clinical practice, 2018 Objectives: Hyperprolactinemia is a common adverse event associated with psychotropic medications (mainly antipsychotics) used in the management of schizophrenia and bipolar disorders.
F. Alosaimi +6 more
semanticscholar +1 more source
Andrology, Volume 13, Issue 4, Page 794-803, May 2025.Abstract Background Cardiovascular disease induces erectile dysfunction modulated by endothelial nitric oxide synthase enzyme and an impaired ejection fraction that restricts penis vascular congestion. However, the mechanisms regulating endothelial dysfunction are not understood.
Ana Segura +7 more
wiley +1 more source
Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center
The Pan African Medical Journal, 2020 Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat +5 more
doaj +1 more source
Clinical guidelines ‘Hyperprolactinemia’ (draft)
Ожирение и метаболизм, 2023 Hyperprolactinemia is a persistent excess of the blood serum prolactin. The syndrome contains various symptoms, the most characteristic is a violation of the reproductive system.
I. I. Dedov +15 more
doaj +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.High‐end normal hemoglobin levels are associated with an increased odds of polycystic ovary syndrome (PCOS), potentially through a mechanism of elevating testosterone levels involving the hypoxia‐inducible factor 1 (HIF‐1) pathway. These findings provide novel insights into the pathophysiology of PCOS and highlight that hemoglobin levels may serve as a
Guiquan Wang +13 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 4, Page 697-706, April 2025.Recurrent pregnancy loss (RPL) is a heterogeneous multifactorial syndrome. A customized management can lead to a good pregnancy outcome in more than a half of cases. Age <40 and AMH >1 ng/mL are the major positive predictors of live birth rate in RPL women.
Chiara Tersigni +11 more
wiley +1 more source
Cabergoline Use and Pregnancy Outcomes: A Systematic Review
Birth Defects Research, Volume 117, Issue 3, March 2025.ABSTRACT Introduction Lack of available expert guidelines leads clinicians to interrupt cabergoline treatment upon confirmation of pregnancy and consider switching to bromocriptine, which is more commonly used during pregnancy but is poorly tolerated.
Anne‐Sophie Otis +4 more
wiley +1 more source