Results 61 to 70 of about 22,618 (258)
ABSTRACT In the 1950s–60s, serotonergic psychedelic drugs were studied as potential adjuvants to psychotherapy to treat addiction and alcoholism. However, starting in the 70s, preclinical and clinical studies on psychedelics stopped for decades because legislation controlled its recreational use, citing their hallucinogenic and psychotomimetic effects,
Makiath Adebo+9 more
wiley +1 more source
Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center
Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat+5 more
doaj +1 more source
ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain+11 more
wiley +1 more source
Hyperprolactinemia (HP) is a persistent increase in serum prolactin levels, the most typical manifestation of which is a dysfunction of the reproductive system.
T. D. Zadorozhna+3 more
doaj +1 more source
Surveying 300 neurologists, psychiatrists, and family physicians, this study demonstrates discipline‐specific strengths‐imaging (neurology), diagnosis (psychiatry), and pharmacological follow‐up (family medicine)‐yet persistent gaps in holistic care of late‐onset bipolar disorder in elders.
Yagmur Sever Fidan+6 more
wiley +1 more source
Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia
Objective. We compared the characteristics of patients with Cushing’s disease alone with those of patients with Cushing’s disease and hyperprolactinemia. Methods. Eighty-four patients were enrolled between 2002 and 2011, in a hospital in China. Clinical,
Cheng Huan+4 more
doaj +1 more source
Sexual Dysfunction as a Side Effect of Hyperprolactinemia in Methadone Maintenance Therapy [PDF]
Although endocrine abnormalities are recognized in opiate users, very little is known about the range of hormones affected, their pathophysiology and their clinical relevance.
Spasovska Trajanovska, Aneta+4 more
core +1 more source
What's new? Bone metastases are common in a variety of cancer types, causing increased pain and worse outcomes. Suppression of bone turnover, such as with the monoclonal antibody denosumab, results in fewer skeletal complications and improved prognosis. Here, the authors demonstrate the safety and efficacy of a similar antibody, JMT103. Like denosumab,
Ran Ran+15 more
wiley +1 more source
Background Pediatric brain cancer survivors often experience hypothalamic–pituitary dysfunction due to cranial irradiation and chemotherapy. While hormone deficiencies have been studied, the changes in pituitary size and shape on long‐term MRI and their relationship to endocrine dysfunction remain under‐explored.
Feras Qawasmi+8 more
wiley +1 more source
Association of polymorphic variants of DRD2 and DRD3 genes with development of neuroleptic hyperprolactinemia in patients with schizophrenia [PDF]
Hyperprolactinemia is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine receptors in the pituitary gland. We describe the association between hyperprolactinemia and a set of SNPs from DRD2 and DRD3 receptor genes
Бойко, А. С.+2 more
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