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Afebrile vancomycin-induced delayed hypersensitivity suggestive of incomplete drug rash with eosinophilia and systemic symptoms syndrome: a case report [PDF]
Journal of Medical Case ReportsBackground Vancomycin-induced delayed hypersensitivity reactions are rare and typically accompanied by systemic symptoms such as fever, eosinophilia, and organ dysfunction, known as drug reaction with eosinophilia and systemic symptoms syndrome. However,
Chien-Hung Chou +3 more
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Biomedicines, 2023 Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu +3 more
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DELAYED HYPERSENSITIVITY [PDF]
The Journal of Experimental Medicine, 1968 Exposure to picryl guinea pig albumin with 3–6 picryl groups per mole failed to affect the ability of peritoneal exudate or peripheral blood leukocytes from sensitized donors to transfer delayed sensitivity to normal recipients. In contrast, conjugates containing 40–48 picryl groups per mole altered the ability of exposed leukocytes to transfer delayed
John P Phair, Fred S Kantor
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Swiss Medical Weekly, 2023 BACKGROUND: Corticosteroids, which are anti-inflammatory and immunosuppressive agents used for the treatment of various diseases including allergic disorders, can induce immediate and delayed hypersensitivity reactions.
Keren Mahlab-Guri +2 more
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Pharmacological prevention of delayed hypersensitivity reactions caused by iodinated contrast media
World Allergy Organization Journal, 2021 Background: Delayed hypersensitivity reactions (DHRs) to radiocontrast media (RCM) occur in approximately 0.5–23.0% of patients and are thought to be caused by T cell-mediated mechanisms. However, an optimal pharmacological preventive strategy is not yet
Jung-Hyun Kim +7 more
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Allergology International, 2022 Background: Skin rash often occurs upon oral administration of amoxicillin in children, due to non-immediate hypersensitivity. However, information on delayed hypersensitivity to amoxicillin is scarce.
Yukiko Katoh +5 more
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Delayed hypersensitivity reaction to allopurinol: A case report [PDF]
Malaysian Family Physician, 2023 Allopurinol is the well-known first-line treatment option for symptomatic hyperuricaemia and gout. It is cost-effective particularly for the management of chronic gout.
Mohammad Che Man +5 more
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Delayed Hypersensitivity [PDF]
Science, 1960 The capacity to develop the delayed type of hypersensitivity to diphtheria toxoid and ovalbumin may persist in guinea pigs and rabbits that have received doses of x-ray sufficient to eliminate a detectable antibody response. Larger doses of x-irradiation can prevent development of delayed-type hypersensitivity in rabbits.
A J, Crowle +3 more
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DELAYED HYPERSENSITIVITY [PDF]
The Journal of Experimental Medicine, 1958 Guinea pigs with delayed hypersensitivity to protein antigens show a specific febrile response accompanied by a lymphopenia following injection of a desensitizing dose of specific antigen. No signs of shock are observed in highly sensitive animals following this injection.
Jonathan W. Uhr, M. W. Brandriss
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Tools to improve the diagnosis and management of T-cell mediated adverse drug reactions
Frontiers in Medicine, 2022 Delayed drug T-cell immune-mediated hypersensitivity reactions have a large clinical heterogeneity varying from mild maculopapular exanthema (MPE) to severe cutaneous adverse reactions (SCARs) such as acute generalized exanthematous pustulosis (AGEP ...
Ana Maria Copaescu +8 more
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