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Hypersensitivity, Delayed Type*
2005Hypersensitivity reactions occur when the immune system acts in an exaggerated manner leading to tissue damage. Delayed hypersensitivity is an immunologic reaction that is mediated primarily by T cells and monocytes and presents hours to days after the antigen crosses into the skin.
L. A. Burns-Naas
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Current Protocols in Immunology, 2001
AbstractDelayed‐type hypersensitivity (DTH) is an in vivo assay of cell‐mediated immune function. DTH reactions are often divided into two phases: the sensitization phase, referring to the initial immunization with specific antigen, and the efferent or challenge phase of the DTH response, which usually follows 6 to 14 days after sensitization.
Y, Luo, M E, Dorf
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AbstractDelayed‐type hypersensitivity (DTH) is an in vivo assay of cell‐mediated immune function. DTH reactions are often divided into two phases: the sensitization phase, referring to the initial immunization with specific antigen, and the efferent or challenge phase of the DTH response, which usually follows 6 to 14 days after sensitization.
Y, Luo, M E, Dorf
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Impaired Delayed Hypersensitivity
JAMA: The Journal of the American Medical Association, 1968To the Editor:— I was very much interested in the report of Waldorf et al (203:831, 1968) concerning the impairment in skin reactivity of older individuals after the induction of delayed skin test reactions by the application of patch tests of 2, 4-dinitrochlorobenzene (DNCB).
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Journal of Immunology, 1987
We have previously shown that at least two types of Lyt-1+, Lyt-2-, L3T4+ helper T cell clones can be distinguished in vitro by different patterns of lymphokine secretion and by different forms of B cell help.
D. Cher, T. Mosmann
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We have previously shown that at least two types of Lyt-1+, Lyt-2-, L3T4+ helper T cell clones can be distinguished in vitro by different patterns of lymphokine secretion and by different forms of B cell help.
D. Cher, T. Mosmann
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The Journal of Immunology, 1969
Summary Pre-exposure of sensitized guinea pig peritoneal exudate cells to antigen renders them incapable of migration inhibition in capillary tubes. However, pre-exposure to the same antigen did not affect migration inhibition of heterologously sensitized cells.
Eleanor A Lipsmeyer, Fred S Kantor
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Summary Pre-exposure of sensitized guinea pig peritoneal exudate cells to antigen renders them incapable of migration inhibition in capillary tubes. However, pre-exposure to the same antigen did not affect migration inhibition of heterologously sensitized cells.
Eleanor A Lipsmeyer, Fred S Kantor
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Delayed hypersensitivity to bosentan
Allergy, 2009This is the first case of a cell-mediated hypersensitivity to bosentan diagnosed on the basis of positive responses to the lymphocyte transformation test and a challenge. However, the latter provoked a severe reaction (DRESS)
A. Romano +5 more
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Delayed hypersensitivity to flurbiprofen
Journal of Internal Medicine, 1997Immune‐mediated reactions to nonsteroidal antiinflammatory drugs (NSAIDs) are unusual, and true allergy to the drug flurbiprofen has never been documented. We observed a patient who developed a maculopapular rash 48 h after beginning oral therapy with this drug, and 2 days later, angioedema and hypotension.
A, Romano, F, Pietrantonio
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