Results 31 to 40 of about 149 (148)

Late‐onset asystole associated with vagal nerve stimulation

Epilepsia Open, EarlyView.
Abstract Vagal nerve stimulation (VNS) is a form of neuromodulation that is an established adjunct in the management of drug‐resistant epilepsy. The common side effects of VNS are cough, dysphonia, or shortness of breath, which are often mild and do not require discontinuation of therapy.
Divya Nagabushana, Huan Huynh, Mark D. McCauley, Anna Serafini   +3 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Self‐Warning and Self‐Repairing Mechanisms in Functional Coatings: A Review

Exploration, EarlyView.
In this paper, we summarize the research progress of self‐warning and self‐repairing coatings in the field of metal corrosion protection as much as possible from the perspective of functional material selection. Meanwhile, the current progress of substituting dual‐functional coatings for single‐functional coatings is also highlighted. ABSTRACT Coatings
Yixin Chen, Qian Wang, Lifeng Hou, Hao Huang, Zhiqiang Gao, Yinghui Wei   +5 more
wiley   +1 more source

Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding

IJU Case Reports, EarlyView.
ABSTRACT Introduction Enfortumab vedotin (EV) has been reported to cause skin toxicity in some patients. We report a rare case of toxic epidermal necrolysis (TEN) induced by EV and complicated by severe gastrointestinal (GI) bleeding. Case Presentation A 70‐year‐old man with recurrent urothelial carcinoma developed a trunk rash at 16 days after EV ...
Aika Matsuyama, Takashi Kato, Rion Kawase, Mikinori Kobayashi, Ayako Momota, Yukiko Tsunoda, Asaomi Yamaguchi, Hiroki Hirabayashi, Shoji Suzuki, Masashi Kato   +9 more
wiley   +1 more source

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

Journal of Biophotonics, EarlyView.
Photoactivated chemotherapy (PACT), an oxygen‐independent light‐based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target‐specific activation while minimizing off‐target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that ...
Nkune Williams Nkune, Heidi Abrahamse
wiley   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

Journal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Examining the Impact of Diet‐and‐Exercise‐Induced Weight Loss on Drug Metabolism and Gastric Emptying in Patients with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Obesity significantly influences drug pharmacokinetics (PK), which challenges optimal dosing. This study examines the effects of diet‐and‐exercise‐induced weight loss on key drug‐metabolizing enzymes and gastric emptying in patients with obesity, who frequently require medications for comorbidities.
Shuhan Liu, Lu Wang, Nicole Miller, Andrea Waltje, Mohamed Abdelnabi, Hao‐Jie Zhu, Duxin Sun, Amy E. Rothberg, Manjunath P. Pai   +8 more
wiley   +1 more source

Pharmacokinetic Characterization of Iopamidol and Iohexol for Optimizing Measured Glomerular Filtration Rate Assessment in Clinical Practice and Drug Development

The Journal of Clinical Pharmacology, EarlyView.
Abstract Accurate kidney function assessment supports healthcare and clinical decision‐making in practice and drug development. Measured glomerular filtration rate (mGFR) via iohexol clearance is the gold standard, but cost, supply issues, and logistical challenges limit its clinical use.
Levi Hooper, Michael Heung, Lu Wang, Aleksas Matvekas, Radin Alikhani, Michael T. Kenes, Kathleen A. Stringer, Bruce A. Mueller, Manjunath P. Pai   +8 more
wiley   +1 more source

Genetically‐targeted control of the spinal cord and peripheral nervous system

Journal of Intelligent Medicine, EarlyView.
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano, Victoria Koptelova, Zoya Ahmad, Huiliang (Evan) Wang   +3 more
wiley   +1 more source

State‐of‐the‐art review of blenderized diets—Status and future directions

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract This state‐of‐the‐art review was produced by a multidisciplinary team composed of pediatric gastroenterology and nutrition healthcare providers to provide a comprehensive overview of the use of blenderized tube feeds (BTFs). The team developed 12 vital questions to address gaps in the current understanding and practice of using BTFs, then ...
Sharon Weston, Anushree Algotar, Sara Karjoo, Megan Gabel, Patrice Kruszewski, Debora Duro, Senthilkumar Sankararaman, Danielle Wendel, Shweta S. Namjoshi, Ruba A. Abdelhadi, David Kawatu, Mark R. Corkins, Timothy Sentongo   +12 more
wiley   +1 more source