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Hypersensitivity pneumonitis [PDF]

Nature Reviews Disease Primers, 2020
This PrimeView highlights the mechanisms underlying Hypersensitivity pneumonitis, which is a syndrome caused by the inhalation of a variety of environmental antigens in susceptible and sensitized individuals.
Ulrich Costabel, Yasunari Miyazaki, Annie Pardo   +2 more
exaly   +9 more sources

Chronic hypersensitivity pneumonitis is associated with an increased risk of venous thromboembolism: a retrospective cohort study

BMC Pulmonary Medicine, 2021
Background Idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis share commonalities in pathogenesis shifting haemostasis balance towards the procoagulant and antifibrinolytic activity.
Małgorzata Sobiecka, Monika Szturmowicz, Katarzyna Lewandowska, Agata Kowalik, Ewa Łyżwa, Katarzyna Zimna, Inga Barańska, Lilia Jakubowska, Jan Kuś, Renata Langfort, Witold Tomkowski   +10 more
doaj   +2 more sources

Diagnosis of Hypersensitivity Pneumonitis in Adults: An Official ATS/JRS/ALAT Clinical Practice Guideline

American Journal of Respiratory and Critical Care Medicine, 2020
Background: This guideline addresses the diagnosis of hypersensitivity pneumonitis (HP). It represents a collaborative effort among the American Thoracic Society, Japanese Respiratory Society, and Asociación Latinoamericana del Tórax. Methods: Systematic
Ganesh Raghu, Martine Remy-Jardin, Christopher J Ryerson, Mas   +2 more
exaly   +2 more sources

Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures

American Journal of Respiratory and Critical Care Medicine, 2020
RATIONALE Chronic hypersensitivity pneumonitis (CHP) is caused by an immune response to antigen inhalation and is characterized by variable histopathological and clinical features.
Haruhiko Furusawa, Tsukasa Okamoto, Jonathan S Kurche   +2 more
exaly   +2 more sources

Concomitant diagnosis of hypersensitivity pneumonitis and localized epithelioid mesothelioma: a rare case report [PDF]

Einstein (São Paulo)
Hypersensitivity pneumonitis is an inflammatory lung disease caused by antigen inhalation after sensitization. Here, we report a rare case of the simultaneous diagnosis of hypersensitivity pneumonitis and epithelioid mesothelioma, a subtype of malignant ...
Simone de Leon Martini, Thiago Krieger Bento da Silva, Bianca Canela Furian, Ana Carolina Storch Klein, Júlia Gabriela Storch Klein, Camila Samrsla Möller, Dâmaris Manfro Pinto Garcia, Guilherme Bohm Ferreira   +7 more
doaj   +2 more sources

Rituximab therapy in patients with treatment-refractory hypersensitivity pneumonitis [PDF]

Scientific Reports
Hypersensitivity pneumonitis (HP) presents with a highly variable clinical course, and traditional treatment includes systemic corticosteroids and strict antigen avoidance.
Yosri Akl, Safy Zahid Kaddah, Shereen Medhat Nassar, Rana Kamal EL Said   +3 more
doaj   +2 more sources

Clinical predictors of physiologic change after treatment with immunosuppression in hypersensitivity pneumonitis. [PDF]

PLoS ONE
IntroductionTreatment of hypersensitivity pneumonitis involves removal of the antigen and may include the use of immunosuppression or antifibrotic therapy.
Margaret Kypreos, Esther de Boer, Graham Ellington, Genichiro Fujioka, Jerry Liu, Craig Glazer, Traci Adams   +6 more
doaj   +2 more sources

Management and Resolution of Hypersensitivity Pneumonitis-Related Events in Japanese Patients Treated with Amikacin Liposome Inhalation Suspension in the CONVERT and INS-312 Clinical Trials [PDF]

Infectious Diseases and Therapy
In the phase 3 CONVERT trial, amikacin liposome inhalation suspension (ALIS) plus guideline-based therapy (GBT) achieved greater culture conversion than GBT alone in the treatment of refractory Mycobacterium avium complex pulmonary disease (MAC-PD).
Yoshitaka Yamazaki, Taku Nakagawa, Zhanna Jumadilova, Dayton Yuen, Raul Villa, Naoki Hasegawa   +5 more
doaj   +2 more sources

Diagnosis, course and management of hypersensitivity pneumonitis

European Respiratory Review, 2022
Hypersensitivity pneumonitis (HP) is a complex and heterogeneous interstitial lung disease (ILD) that occurs when susceptible individuals develop an exaggerated immune response to an inhaled antigen.
M. Hamblin, H. Prosch, M. Vašáková
semanticscholar   +1 more source

Diagnosis and Evaluation of Hypersensitivity Pneumonitis: CHEST Guideline and Expert Panel Report.

Chest, 2021
BACKGROUND The purpose of this analysis is to provide evidence-based and consensus-derived guidance for clinicians to improve individual diagnostic decision-making for hypersensitivity pneumonitis (HP) and decrease diagnostic practice variability ...
Evans R. Fernández Pérez, W. Travis, D. Lynch, K. Brown, Kerri A Johannson, M. Selman, J. Ryu, A. Wells, Yuh-Chin Tony Huang, C. Pereira, M. Scholand, A. Villar, N. Inase, R. B. Evans, S. Mette, Lindsy Frazer-Green   +15 more
semanticscholar   +1 more source