Results 181 to 190 of about 2,776,276 (310)

Nerandomilast and the Evolving Therapeutic Paradigm in Pulmonary Fibrosis: From Mechanism to Clinical Efficacy

open access: yesiNew Medicine, EarlyView.
Therapeutic mechanism, clinical efficacy and future directions for nerandomilast in pulmonary fibrosis. ABSTRACT The recent Phase III FIBRONEER trials establish nerandomilast, a novel oral phosphodiesterase 4B (PDE4B) inhibitor, as an effective therapy for idiopathic and progressive pulmonary fibrosis. By elevating cyclic adenosine monophosphate (cAMP),
Qianwen Bai   +4 more
wiley   +1 more source

Profiles of Social Status Among at‐Risk Adolescents in a Residential Setting: A Person‐Centered Approach

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Adolescents often care about their social status which may be influenced by various personality and behavioral characteristics. This study used a person‐centered approach to examine intrapersonal (i.e., psychopathy, narcissism, self‐esteem) and interpersonal (i.e., aggression, prosocial behavior) factors associated with how ...
Hyunah Kim   +2 more
wiley   +1 more source

Severe Delayed Hypersensitivity Reaction at Guselkumab Injection Site. [PDF]

open access: yesContact Dermatitis
Allichon S   +9 more
europepmc   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura   +11 more
wiley   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

open access: yesJournal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Normative scores and clinical cut‐offs of the Cyclothymic–Hypersensitive Temperament Questionnaire in adolescence

open access: yesJCPP Advances, EarlyView.
Abstract Background The Cyclothymic–Hypersensitive Temperament (CHT) is a multidimensional, transdiagnostic affective disposition characterized by mood instability, interpersonal sensitivity, heightened emotional reactivity and impulsive behaviors. The CHT Questionnaire (CHTQ) currently lacks of normative references and empirically derived thresholds ...
Anna Pezzella   +10 more
wiley   +1 more source

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