Results 231 to 240 of about 2,776,276 (310)

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

open access: yesNeuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng   +12 more
wiley   +1 more source

Risk of septic arthritis following corticosteroid and platelet‐rich plasma injections: A multicenter retrospective review

open access: yesPM&R, EarlyView.
Abstract Background Platelet‐rich plasma injections (PRPI) are a relatively new and evolving treatment option for a variety of musculoskeletal injuries. It has been theorized that there is an increased risk of septic arthritis (SA) with PRPI, though there have been no dedicated studies to assess the incidence of SA and only three cases have been ...
Kory Ford   +4 more
wiley   +1 more source

Allergen‐Functionalized Microfluidic Immunoadsorption Platform for Selective Depletion of Peanut‐Specific Antibodies From Whole Blood

open access: yesJournal of Polymer Science, EarlyView.
We present a microfluidic immunoadsorption platform functionalized with a layer‐by‐layer (LbL) nanofilm composed of poly(diallyldimethylammonium chloride) (PDDA) and protein extract (PE) for selective capture of peanut‐specific antibodies directly from the whole blood obtained from a peanut allergy mouse model.
Hesaneh Ahmadi   +4 more
wiley   +1 more source

A composite, host‐participatory haustorium links host compatibility to defence bifurcation in Alectra vogelii (Orobanchaceae)

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Parasitic weeds of the family Orobanchaceae are among the most damaging constraints on food production in the tropics, draining water and nutrients from their hosts and threatening the livelihoods of millions of smallholder farmers. Yellow witchweed (Alectra vogelii) can destroy entire legume harvests across sub‐Saharan Africa, where these crops are a ...
Hildah Kithinji   +2 more
wiley   +1 more source

Comprehensive analysis of microtubule‐inhibiting herbicides reveals shared subcellular phenotypes and distinct resistance profiles

open access: yesPest Management Science, EarlyView.
Using cellular phenotyping and resistance profiling, we show that herbicides across the Herbicide Resistance Action Committee (HRAC) Groups 3 and 23 induce indistinguishable, dose‐dependent microtubule defects. Resistance patterns, rather than cellular phenotypes, reveal distinct sites of action and support reclassifying Group 3 as α‐tubulin binders ...
Katharina Kaprocki   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy