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Clinical Pharmacology & Therapeutics, 1974
There are many well‐known hypersensitivity reactions to drugs such as penicillin and sulfa drugs, but this paper will emphasize other aspects of hypersensitivity reactions to drugs that are not as widely known. Certain drugs such as hydralazine and procainamide are widely used in the treatment of hypertension and cardiac arrhythmia.
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There are many well‐known hypersensitivity reactions to drugs such as penicillin and sulfa drugs, but this paper will emphasize other aspects of hypersensitivity reactions to drugs that are not as widely known. Certain drugs such as hydralazine and procainamide are widely used in the treatment of hypertension and cardiac arrhythmia.
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Hypersensitivity reactions to trimetrexate
Investigational New Drugs, 1990Trimetrexate is a nonclassical antifol currently being tested for efficacy in cancer patients and as an antiparasitic agent against Pneumocystis carinii pneumonia in AIDS patients. We have now received the first reports of hypersensitivity reactions in Phase II cancer trials. Two types of reactions were noted.
Grem, J. L. +3 more
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Hypersensitivity reactions to cephalosporins
Expert Opinion on Drug Safety, 2008At present, cephalosporins represent one of the most prescribed classes of antibiotics. Although allergic reactions have been estimated to be infrequent, the number of reactions to cephalosporins is increasing due to their wide use. Cross-reactivity with penicillins has mainly been evaluated in patients with penicillin allergy.
Esther, Moreno +5 more
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Hypersensitivity reaction to desipramine
Journal of Allergy and Clinical Immunology, 1987Adverse reactions to the tricyclic antidepressant drugs imipramine and desipramine have been described and include eosinophilia, pulmonary infiltrates with eosinophilia, and elevated total serum IgE levels. The immunologic mechanism accounting for these adverse reactions has not been elucidated. This article describes a patient manifesting bronchospasm,
J R, Panuska +3 more
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Hypersensitivity Reactions to Anticonvulsants
Current Allergy and Asthma ReportsAntiepileptics are the mainstay of treatment for seizure management. Immediate and delayed hypersensitivity reactions associated with antiepileptics are common. It is important to differentiate between these reactions as management and prognosis varies.This review article aims to describe the types of hypersensitivity reactions reported with ...
Unaiza, Faizan, Allison, Ramsey
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Incidence of Hypersensitivity Reactions
The Annals of Thoracic Surgery, 1998Aprotinin is a naturally occurring serine protease inhibitor derived from bovine lung. In common with all foreign proteins, it possesses antigenic properties and has the possibility of allergic reactions on reexposure.Data are presented on the incidence of adverse reactions to aprotinin and the time course of antibody development after initial exposure.
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Hypersensitivity reactions to quinolones
Current Opinion in Allergy & Clinical Immunology, 2011The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones.Hypersensitivity reactions to quinolones, especially anaphylactic reactions, have become more common in the past ...
Blanca-López N +2 more
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Carboplatin Hypersensitivity Reactions
Clinical Journal of Oncology Nursing, 2006Carboplatin is used widely to treat cancers such as lung, breast, and ovarian. Hypersensitivity reactions (HSRs) to carboplatin can occur, often after numerous doses. The reactions can range from mild to life threatening. Oncology nurses witness the reactions and are instrumental in providing interventions to assist patients. Symptoms include flushing,
Debra, Winkeljohn, Martha, Polovich
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Hypersensitivity Reaction to Lignocaine
Journal of The Royal Naval Medical Service, 1971Abstract A case is described of a hypersensitivity reaction resulting from the administration of a dental local anaesthetic.
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Hypersensitivity reactions to heparins
Current Opinion in Allergy & Clinical Immunology, 2016Purpose of review This article provides an update on hypersensitivity reactions to heparins and novel oral anticoagulants, with special emphasis on diagnostic methods and management of patients. Recent findings Although heparins are drugs widely used, hypersensitivity reactions are ...
Purificación, Gonzalez-Delgado +1 more
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