Results 131 to 140 of about 376,610 (219)

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

open access: yesiNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma   +5 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

Diagnostic Pitfalls and Lessons Learned in Portal Hypertension. [PDF]

open access: yesACG Case Rep J
Mannava A, Liu W, Saab S, Ramkissoon R.
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li   +3 more
wiley   +1 more source

Asprosin as a Potential Link Between Vascular Inflammation and Disease Activity in Behçet's Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum asprosin levels are significantly elevated in patients with Behçet's disease compared to healthy controls. Asprosin concentrations increase progressively with disease activity and are strongly associated with vascular involvement and uveitis, suggesting a potential role as a biomarker of vascular inflammation and disease severity.
Zeynep Kaya   +6 more
wiley   +1 more source

Age‐Associated Variations in Complete Blood Cell Count Parameters and Derived Indices Among Community‐Dwelling Chinese Older Adults

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This cross‐sectional study analyzed data from 9331 participants aged 24–97 to characterize age‐ and sex‐related physiological trajectories of complete blood cell count (CBC) parameters and derived inflammatory indices. Key findings encompassed age‐related declines in red blood cell and platelet counts, elevations in RDW‐CV indices and monocyte ...
Xiangyi Ma   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy