Results 81 to 90 of about 435,750 (303)

Metformin reverses development of pulmonary hypertension via aromatase inhibition [PDF]

, 2016
Females are more susceptible to pulmonary arterial hypertension than males, although the reasons remain unclear. The hypoglycemic drug, metformin, is reported to have multiple actions, including the inhibition of aromatase and stimulation of AMP ...
Dean, Afshan, Loughlin, Lynn, MacLean, Margaret R., Nilsen, Margaret, Salt, Ian P.   +4 more
core   +2 more sources

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Clinical Characteristics of Geriatric Asthma in Guangxi of China: A Retrospective Comparative Descriptive Study

AGING MEDICINE, EarlyView.
Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu, Qixiang Sun, Yujia Huang, Yuetian Deng, Xiaohong Jiang   +4 more
wiley   +1 more source

Recurrent malignant juxtaglomerular cell tumor: A rare cause of malignant hypertension in a child

Journal of Indian Association of Pediatric Surgeons, 2011
A juxtaglomerular cell tumor or reninoma is a very rare renin-secreting tumor of the kidney and can be an unusual cause of secondary hypertension. We report a case of recurrence of this uncommon tumor at the hilum of left kidney in an 8-year-old male ...
Altaf H Shera, Aejaz A Baba, Iftikhar H Bakshi, Iqbal A Lone   +3 more
doaj   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Brunkhorst, Robert, Förch, Christian, Mayer, Christoph, Niessner, Marion, Pfeilschifter, Waltraud, Steinmetz, Helmuth   +5 more
core   +2 more sources

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source

Treatment responses to antiangiogenetic therapy and chemotherapy in nonsecreting paraganglioma (PGL4) of urinary bladder with SDHB mutation: a case report [PDF]

, 2018
Paraganglioma (PGL) is a rare neuroendocrine tumor. Currently, the malignancy is defined as the presence of metastatic spread at presentation or during follow-up.
Aschelter, Am, Capriotti, G, Cerquetti, L, Lardo, P, Marchetti, P, Matarazzo, I, Nardone, Mr, Petrangeli, E, Schiavi, F, Stigliano, A, Toscano, V   +10 more
core   +1 more source

Association of a Multimodal Perioperative Care Program With Postoperative Complications in Elderly Patients Undergoing Gastrectomy for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya, Hiroshi Fuseya, Yusuke Yonenaga, Keiko Sanada, Toshimi Inano, Yumi Oguma, Kazuko Nakajima, Chikako Ando, Kumiko Oka, Yusuke Koseki, Kenichiro Furukawa, Yutaka Tanizawa, Masanori Terashima, Etsuro Bando   +13 more
wiley   +1 more source

Percutaneous transhepatic portal vein stenting in a patient with benign non-transplant postoperative portal vein stenosis: A case report

Indian Journal of Radiology and Imaging, 2013
Extrahepatic portal vein stenosis is caused by a variety of benign and malignant diseases and results in development of symptoms due to portal hypertension.
KS Madhusudhan, Nikhil Agrawal, Deep N Srivastava, Sujoy Pal, Arun K Gupta   +4 more
doaj   +1 more source

A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]

, 2015
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio, Leto, Antonino, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Silvestri, Luigi   +6 more
core   +1 more source