Results 191 to 200 of about 639,073 (304)

Prognostic Role of Platelets in Pulmonary Arterial Hypertension. [PDF]

Pulm Circ
Fernandes CJCDS, Nascimento IAO, Oliveira T, Jardim CVP, Hoette S, de Souza R.   +5 more
europepmc   +1 more source

Intravascular Lithotripsy for Coral Reef Aorta and Chronic Mesenteric Ischemia: Case Report and Comprehensive Literature Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Chronic mesenteric ischemia (CMI) secondary to extensive paravisceral atherosclerosis is a rare but challenging vascular condition, often presenting with postprandial abdominal pain, weight loss, and claudication due to impaired blood flow. While surgical bypass is a standard treatment, it carries significant risks, particularly in patients ...
Dipankar Mukherjee, Bibhas Amatya, David J. Spinosa   +2 more
wiley   +1 more source

Administration of Nebulized Nitroglycerin Inhalation Combined With Subarachnoid Anesthesia for Cesarean Delivery With Pulmonary Arterial Hypertension: A Case Report. [PDF]

Clin Case Rep
Xin L, Hu C, Qian Y, Lu S, Xu J, Gu Z.
europepmc   +1 more source

Clinical Outcomes Post‐Transcatheter Aortic Valve Replacement in Patients With Hypertrophic Obstructive Cardiomyopathy

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Patients with hypertrophic obstructive cardiomyopathy (HOCM) were excluded from all major trials for transcatheter aortic valve replacement (TAVR). “Suicide left ventricle” occurring after TAVR is postulated to occur as a result of chronic pressure overload from fixed obstruction that is acutely relieved after the valve deployment ...
Muhammad Usman Almani, Vibhor Ahluwalia, Muhammad Yousuf, Jafar Alzubi, Mohammad Hamza, Raphael Bonita, Christian Witzke   +6 more
wiley   +1 more source

The Correlation Between NLR, RDW, and Pulmonary Hypertension in Patients With Bronchiectasis and Chronic Obstructive Pulmonary Disease Overlap Syndrome. [PDF]

Clin Respir J
Hu L, Liu Z, Yu J, Yang Z, Feng D.
europepmc   +1 more source

A Comparison of a Drug Coated Balloon With Drug Eluting Stent Strategy for Treating Coronary Bifurcation Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The treatment of coronary bifurcation lesions (CBL) remains complex and associated with a higher rate of long‐term adverse cardiovascular events due to anatomical and procedural complexity. Aims We compared procedural outcomes between a drug coated balloon (DCB) only approach and a 2nd generation drug eluting stent (DES) for ...
Natasha Corballis, Ioannis Merinopoulos, U. Bhalraam, Tharusha Gunawardena, Vasiliki Tsampasian, Rajkumar Natarajan, Upul Wickramarachchi, Mohamed Mohamed, Allan Clark, Mamas A. Mamas, Vassilios S. Vassiliou, Simon Eccleshall, SPARTAN‐Norfolk Consortium, Tim Gilbert, Clint Maart, Johannes Reinhold, Paul Richardson, Alisdair Ryding, Trevor Wistow, Chris Sawh, Sulfi Sreekumar   +20 more
wiley   +1 more source

Neonatal pulmonary hypertension in the NICU: a 10-year single-center experience. [PDF]

BMC Pediatr
Ay O, Gunes S, Erfidan E, Simsek A.
europepmc   +1 more source

Development of Keap1‐Nrf2 Protein–Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene‐2‐acetamide Scaffold, and its Anti‐Inflammatory Effects

ChemMedChem, EarlyView.
Pyrrolidine‐type naphthalene‐2‐acetamide compound 5i inhibits Kelch‐like ECH‐associated protein 1 (Keap1)‐nuclear factor erythroid 2‐related factor 2 (Nrf2) protein–protein interaction by binding to the Keap1‐DC domain; it subsequently activates intracellular Nrf2 and induces Nrf2‐target genes.
Daisuke Yasuda, Kai Toyoshima, Koujin Kojima, Hanako Ishida, Kazuma Kaitoh, Riyo Imamura, Kayoko Kanamitsu, Hirotatsu Kojima, Megumi Funakoshi‐Tago, Masanori Osawa, Tomoyuki Ohe, Tomoya Hirano   +11 more
wiley   +1 more source

Phenotyping of patients with mild pulmonary hypertension. [PDF]

Open Heart
Dardi F, Bertozzi R, Ballerini A, Cennerazzo F, Donato F, Guarino D, Manes A, Nardi E, Palazzini M, Galié N.   +9 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source