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Pulmonary Hypertension [PDF]

open access: yesJAMA, 2021
Pulmonary hypertension is the term used to describe a group of disorders characterized by abnormally high pressures in the pulmonary arteries. Initial evaluation is focused on identifying the cause, which helps guide appropriate treatment.
D. Poch, J. Mandel
semanticscholar   +3 more sources

Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension.

New England Journal of Medicine, 2023
BACKGROUND Pulmonary arterial hypertension is a progressive disease involving proliferative remodeling of the pulmonary vessels. Despite therapeutic advances, the disease-associated morbidity and mortality remain high.
M. Hoeper   +20 more
semanticscholar   +1 more source

Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review.

Journal of the American Medical Association (JAMA), 2022
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension (PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is approximately 10.6 cases per 1 million adults in the US.
N. Ruopp, B. Cockrill
semanticscholar   +1 more source

Pulmonary Arterial Hypertension.

New England Journal of Medicine, 2021
Copyright © 2021 Massachusetts Medical Society. Pulmonary hypertension is a syndrome characterized by marked remodeling of the pulmonary vasculature and a progressive rise in the pulmonary vascular load, leading to hypertrophy and remodeling of the right
P. Hassoun
semanticscholar   +1 more source

Molecular genetic framework underlying pulmonary arterial hypertension

Nature Reviews Cardiology, 2019
Laura Southgate   +2 more
exaly   +2 more sources

Pulmonary hypertension

Drugs of Today, 1998
Pulmonary hypertension can be caused by an increase in pulmonary blood flow, an increase in left-heart impedance or an increase in pulmonary vascular resistance. Although there are many specific causes that have been identified, clinical presentation and natural history are common to all etiologies.
D, Moraes, J, Loscalzo
openaire   +2 more sources

Pulmonary Hypertension

Medical Clinics of North America, 2019
Pulmonary hypertension (PH) is a chronic and progressive disease that presents like many other lung diseases, often leading to a delay in diagnosis, and therefore a delay in optimal therapy. This article provides a review of PH for internists, covering clinical presentation, diagnostic algorithm, different types of PH, and overview of treatments.
Darlene, Kim, M Patricia, George
openaire   +2 more sources

Congenital diaphragmatic hernia-associated pulmonary hypertension.

Seminars in Perinatology, 2020
Congenital diaphragmatic hernia (CDH) is a neonatal pathology in which intrathoracic herniation of abdominal viscera via diaphragmatic defect results in aberrant pulmonary and cardiovascular development.
Vikash S. Gupta, M. Harting
semanticscholar   +1 more source

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