Results 141 to 150 of about 2,534,413 (315)

Ambulatory Blood Pressure in Chronic Kidney Disease: Ready for Prime Time?

Kidney International Reports, 2016
Hypertension is common in patients with chronic kidney disease (CKD) and is the most important modifiable risk factor for CKD progression and adverse cardiovascular events in these patients.
Manuel T. Velasquez, Srinivasan Beddhu, Ehsan Nobakht, Mahboob Rahman, Dominic S. Raj   +4 more
doaj   +1 more source

Cardiovascular morbidity and mortality after kidney transplantation [PDF]

, 2014
Kidney transplantation is the optimal treatment for patients with end stage renal disease (ESRD) who would otherwise require dialysis. Patients with ESRD are at dramatically increased cardiovascular (CV) risk compared to the general population.
Jardine, Alan G., Mark, Patrick B., Stoumpos, Sokratis   +2 more
core   +1 more source

Thrombocytopenia and Anemia After Cardiac Surgery

American Journal of Hematology, EarlyView.
Myriam Beshai, Nour Alhomsi, Theodore E. Warkentin   +2 more
wiley   +1 more source

Time‐Dependent Effect of Prophylactic Trimethoprim‐Sulfamethoxazole on the Incidence of Serious Infections in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Target Trial Emulation Study

Arthritis &Rheumatology, EarlyView.
Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim, Jeffrey R. Curtis, Se Rim Choi, Jina Yeo, Min Jung Kim, Yun Jong Lee, Eun Bong Lee, Jun Won Park   +7 more
wiley   +1 more source

Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT

Kidney Medicine
Rationale & Objective: It is well accepted that acute cognitive dysfunction and delirium can occur with severe acute kidney injury (AKI). Recent evidence has indicated AKI can contribute to incident dementia years later.
Kristen L. Nowak, Anna Ostrow, Ester S. Oh, Zhiying You, Michel Chonchol   +4 more
doaj  

Effect of long‐term voclosporin treatment on renal histology in patients with active lupus nephritis with repeat renal biopsies

Arthritis &Rheumatology, Accepted Article.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin, Clarissa Cassol, Samir V. Parikh, Amit Saxena, Neil Solomons, Vanessa Birardi, Ernie Yap, Clint W. Abner, David R.W. Jayne, Robert B. Huizinga   +9 more
wiley   +1 more source

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

Journal of Lipid Research, 2018
Simultaneous activation of bile acid receptors farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5) by INT-767 significantly reduces atherosclerotic formation. In this study, we investigated the effect of simultaneous inactivation
Shinobu Miyazaki-Anzai, Masashi Masuda, Shohei Kohno, Moshe Levi, Yuji Shiozaki, Audrey L. Keenan, Makoto Miyazaki   +6 more
doaj  

Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]

, 2016
Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

Arthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun, Yu Wang, Yongjing Cheng, Dongmei Guo, Jiankang Hu, Dongzhou Liu, Zhengnan Gao, Changgui Li, Yibing Lu, Xiaodan Kong, Yu Liu, Zhenyu Jiang, Bin Yi, Hongfeng Zhang, Baijie Xu, Shihao Yu, Rieko Kokan, Kohei Ishikawa, Mikiko Kawakatsu, Zhuoli Zhang   +19 more
wiley   +1 more source

Adherence and persistence with direct oral anticoagulants by dose regimen: A systematic review

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1096-1113, April 2025.
Introduction Direct oral anticoagulants (DOACs) are used in patients with non‐valvular atrial fibrillation (NVAF) to prevent complications such as embolic events. Poor adherence to DOACs increases the risk of these complications. This manuscript reviews the impact of once‐daily (OD) vs twice‐daily (BID) dosing regimens on adherence and persistence to ...
Raúl Quirós López, Francesc Formiga Pérez, Jan Beyer‐Westendorf   +2 more
wiley   +1 more source