Results 171 to 180 of about 1,525,836 (242)

Maternal deaths in the UK before and during the COVID‐19 pandemic

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
During the COVID‐19 pandemic, there was a significant increase in the rate of maternal mortality, particularly from direct causes of death. This was accompanied by a greater prevalence of mental health and social complexities amongst the women who died, underscoring the importance of maintaining equitable care access during future crises.
Allison Felker, Marian Knight
wiley   +1 more source

Timing of Delivery in Preeclampsia: Time to Reconsider?

open access: yes
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Rebecca Horgan   +5 more
wiley   +1 more source

Reasonable Exceptions From Unreasonable Policies: Requiring Treatment Agreements for Long‐Term Opioid Therapy and Exemptions for Cancer and Terminal Illness

open access: yesBioethics, EarlyView.
ABSTRACT Since drug overdose deaths began increasing in the United States, policy makers and the medical community have developed tools to try to address the crisis. Opioid Treatment Agreements (OTAs) are one such tool which purportedly seek to promote shared decision‐making and informed consent with patients. OTAs are documents that clinicians present
Larisa Svirsky   +6 more
wiley   +1 more source

Increased Pregnancy Complications Among Mothers With Adverse Childhood Experiences: Findings From a Cross‐Sectional Study

open access: yesBirth, EarlyView.
ABSTRACT Background Adverse Childhood Experiences (ACEs) are potentially traumatic events and family challenges that occur during childhood (0–17 years). Extensive research has linked ACEs to adverse effects throughout life. However, recent studies suggest that ACEs may also have intergenerational consequences, influencing pregnancy complications and ...
Mark F. M. Ketelaars   +4 more
wiley   +1 more source

Hypertensive Disorders in Pregnancy: A Comparative Analysis of Clinical Guidelines Across Six High‐Income Countries

open access: yesBirth, EarlyView.
ABSTRACT Background Women in the United States (U.S.) experience higher maternal morbidity and mortality than other high‐income countries, with hypertensive disorders of pregnancy (HDP) among the most common, preventable contributors. Despite evidence supporting pharmacologic intervention, American College of Obstetricians and Gynecologists (ACOG ...
Kortney Floyd James   +5 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

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