Results 251 to 260 of about 156,340 (338)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 6, Page 1271-1287, March 2026.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Neonatal thyrotoxicosis secondary to maternal graves' disease: a case report. [PDF]

open access: yesBMC Pediatr
Elhassan S   +4 more
europepmc   +1 more source

IMpower010: 5‐Year Outcomes of Atezolizumab in Japanese Patients With Resected Stage IB–IIIA Non‐Small Cell Lung Cancer

open access: yesCancer Science, Volume 117, Issue 3, Page 749-758, March 2026.
The global Phase 3 IMpower010 study (NCT02486718) evaluated atezolizumab versus best supportive care (BSC) after complete resection and adjuvant platinum‐based chemotherapy in patients with stage IB–IIIA non‐small cell lung cancer (NSCLC). Here, we report updated efficacy and safety results from the disease‐free survival (DFS) final and overall ...
Morihito Okada   +9 more
wiley   +1 more source

How Temporal Predictability of Threat and Action Preparation Affect Defensive Freezing Responses

open access: yesPsychophysiology, Volume 63, Issue 3, March 2026.
ABSTRACT Defensive responses to threat are critical for survival and often involve freezing‐like behavior, which has been linked to action preparation. However, it remains unclear how this preparatory mechanism is influenced by unpredictable aversive stimuli that are difficult to discriminate or anticipate.
Alina Koppold   +5 more
wiley   +1 more source

Thyroid dysfunction alters gut microbiota composition and alveolar bone levels in female mice

open access: yesPhysiological Reports, Volume 14, Issue 6, March 2026.
Abstract Thyroid hormone dysfunction has been implicated in both bone metabolism and gut microbial composition, yet the interplay between thyroid status, gut microbiota, and alveolar bone homeostasis remains unclear. In this study, female C57BL/6J mice were treated with triiodothyronine (T3) and thyroxine (T4) to induce hyperthyroidism or with ...
Lucia Thompson   +2 more
wiley   +1 more source

Natural course of subclinical hyperthyroidism in primary care in the Netherlands. [PDF]

open access: yesEur Thyroid J
Ursem SR   +6 more
europepmc   +1 more source

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